THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS
The results of surgical treatment of 700 patients with preoperatively detected drug resistance are analyzed. The majority of patients were with fibro-cavernous, cirrhotic tuberculosis, chronic empyema, caseous pneumonia (78.1%). Chemotherapy was performed on individual schemes including MBT sensitiv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
2022-12-01
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| Series: | Сеченовский вестник |
| Subjects: | |
| Online Access: | https://www.sechenovmedj.com/jour/article/view/685 |
| _version_ | 1826572266642604032 |
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| author | O. N. Ots T. V. Agkatsev M. I. Perelman |
| author_facet | O. N. Ots T. V. Agkatsev M. I. Perelman |
| author_sort | O. N. Ots |
| collection | DOAJ |
| description | The results of surgical treatment of 700 patients with preoperatively detected drug resistance are analyzed. The majority of patients were with fibro-cavernous, cirrhotic tuberculosis, chronic empyema, caseous pneumonia (78.1%). Chemotherapy was performed on individual schemes including MBT sensitivity. Glutoxim and Pentaglobin were used as pathogenetic therapy for correction of immunity. Predominant type of resection surgery — 529 (68,6%), surgical interventions — 121 (15.7%), toracostomy or cavernostomy — 54 (7,0%), pleurectomy — 33 (4,3%), operations on the cult of the chief bronchus — 18 (2,3%), mediastinal lymphadenectomy —16 (2,1%). Postoperative complications occurred in 12,9% of cases, mortality was 1,5%. Laboratory established fact of mycobacteria drug resistance had no apparent effect on the number and type of postoperative complications. The results of treatment depended on the prevalence and complications of tuberculosis, concomitant diseases, weakened immune system and the extent of surgical intervention. |
| first_indexed | 2024-04-10T01:18:36Z |
| format | Article |
| id | doaj.art-82796adf00ad471187deba6c6d257ecf |
| institution | Directory Open Access Journal |
| issn | 2218-7332 2658-3348 |
| language | Russian |
| last_indexed | 2025-03-14T12:24:17Z |
| publishDate | 2022-12-01 |
| publisher | Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) |
| record_format | Article |
| series | Сеченовский вестник |
| spelling | doaj.art-82796adf00ad471187deba6c6d257ecf2025-03-02T09:29:59ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482022-12-01021523379THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGSO. N. Ots0T. V. Agkatsev1M. I. Perelman2First MSMU named after I.M. SechenovFirst MSMU named after I.M. SechenovFirst MSMU named after I.M. SechenovThe results of surgical treatment of 700 patients with preoperatively detected drug resistance are analyzed. The majority of patients were with fibro-cavernous, cirrhotic tuberculosis, chronic empyema, caseous pneumonia (78.1%). Chemotherapy was performed on individual schemes including MBT sensitivity. Glutoxim and Pentaglobin were used as pathogenetic therapy for correction of immunity. Predominant type of resection surgery — 529 (68,6%), surgical interventions — 121 (15.7%), toracostomy or cavernostomy — 54 (7,0%), pleurectomy — 33 (4,3%), operations on the cult of the chief bronchus — 18 (2,3%), mediastinal lymphadenectomy —16 (2,1%). Postoperative complications occurred in 12,9% of cases, mortality was 1,5%. Laboratory established fact of mycobacteria drug resistance had no apparent effect on the number and type of postoperative complications. The results of treatment depended on the prevalence and complications of tuberculosis, concomitant diseases, weakened immune system and the extent of surgical intervention.https://www.sechenovmedj.com/jour/article/view/685pulmonary tuberculosismycobacteriaimmune system |
| spellingShingle | O. N. Ots T. V. Agkatsev M. I. Perelman THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS Сеченовский вестник pulmonary tuberculosis mycobacteria immune system |
| title | THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS |
| title_full | THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS |
| title_fullStr | THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS |
| title_full_unstemmed | THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS |
| title_short | THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS |
| title_sort | surgical treatment of pulmonary tuberculosis with the resistance of mycobacteria to drugs |
| topic | pulmonary tuberculosis mycobacteria immune system |
| url | https://www.sechenovmedj.com/jour/article/view/685 |
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