Keep Your Friends Close, but Your Enemies Closer: Role of Acid Sphingomyelinase During Infection and Host Response

Keep Your Friends Close, but Your Enemies Closer: Role of Acid Sphingomyelinase During Infection and Host Response

Breakdown of the inert and constitutive membrane building block sphingomyelin to the highly active lipid mediator ceramide by extracellularly active acid sphingomyelinase is tightly regulated during stress response and opens the gate for invading pathogens, triggering the immune response, developmen...

Full description

Bibliographic Details
Main Authors: Ha-Yeun Chung, Ralf A. Claus
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Medicine
Subjects:
sphingomyelinase (SMase)
ceramide (CER)
sepsis
organ failure (OF)
inhibitor
FIASMA
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.616500/full

Similar Items

Similar Items