Reduced Endothelin-2 and Hypoxic Signaling Pathways in Granulosa-Lutein Cells of PCOS Women
Granulosa-lutein cells (GLCs) from PCOS women display reduced <i>HIF-1α</i> and <i>EDN2</i> levels, suggesting their role in PCOS etiology. Here, we investigated the mechanisms involved in aberrant <i>EDN2</i> expression in PCOS, and its association with <i>...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/15/8216 |