A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman
We report the case of a 40-year-old woman with a history of an opioid use disorder who presented to our emergency department complaining of palpitations, chest pain, and headache after the intramuscular injection of an ophthalmic solution containing tropicamide and phenylephrine (Visumidriatic Pheny...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2023-09-01
|
| Series: | Emergency Care Journal |
| Subjects: | |
| Online Access: | https://www.pagepressjournals.org/index.php/ecj/article/view/11320 |
| _version_ | 1797690280261976064 |
|---|---|
| author | Antonio Agosti Andrea Vercelli Elena Demichele Francesco Mariani Andrea Biagi Stefano Ferraro Gianfranco Cervellin Erika Poggiali |
| author_facet | Antonio Agosti Andrea Vercelli Elena Demichele Francesco Mariani Andrea Biagi Stefano Ferraro Gianfranco Cervellin Erika Poggiali |
| author_sort | Antonio Agosti |
| collection | DOAJ |
| description | We report the case of a 40-year-old woman with a history of an opioid use disorder who presented to our emergency department complaining of palpitations, chest pain, and headache after the intramuscular injection of an ophthalmic solution containing tropicamide and phenylephrine (Visumidriatic Phenylephrine® 100 mg/mL + 5 mg/mL, Visufarma S.p.A., Italy) a few hours earlier for a voluntary purpose. She developed cardiac toxicity with hypertension, tachycardia, and high levels of high-sensitivity cardiac troponin I, which required continuous cardiac monitoring for 48 hours with complete resolution of the cardiac damage without complications. Based on the current literature, this is the first reported case of cardiotoxicity induced by an ophthalmic solution of tropicamide and phenylephrine used intramuscularly for voluntary purposes.
|
| first_indexed | 2024-03-12T01:57:16Z |
| format | Article |
| id | doaj.art-827aa596ff1f49d29027a3025602d6a7 |
| institution | Directory Open Access Journal |
| issn | 2282-2054 |
| language | English |
| last_indexed | 2024-03-12T01:57:16Z |
| publishDate | 2023-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Emergency Care Journal |
| spelling | doaj.art-827aa596ff1f49d29027a3025602d6a72023-09-07T22:57:46ZengPAGEPress PublicationsEmergency Care Journal2282-20542023-09-0110.4081/ecj.2023.11320A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young womanAntonio Agosti0Andrea Vercelli1Elena Demichele2Francesco Mariani3Andrea Biagi4Stefano Ferraro5Gianfranco Cervellin6Erika Poggiali7Emergency Department, Guglielmo da Saliceto Hospital, PiacenzaEmergency Department, Guglielmo da Saliceto Hospital, PiacenzaEmergency Department, Guglielmo da Saliceto Hospital, PiacenzaEmergency Department, Guglielmo da Saliceto Hospital, PiacenzaCardiology Unit, Guglielmo da Saliceto Hospital, PiacenzaCardiology Unit, Guglielmo da Saliceto Hospital, PiacenzaAcademy of Emergency Medicine and Care, PaviaEmergency Department, Guglielmo da Saliceto Hospital, PiacenzaWe report the case of a 40-year-old woman with a history of an opioid use disorder who presented to our emergency department complaining of palpitations, chest pain, and headache after the intramuscular injection of an ophthalmic solution containing tropicamide and phenylephrine (Visumidriatic Phenylephrine® 100 mg/mL + 5 mg/mL, Visufarma S.p.A., Italy) a few hours earlier for a voluntary purpose. She developed cardiac toxicity with hypertension, tachycardia, and high levels of high-sensitivity cardiac troponin I, which required continuous cardiac monitoring for 48 hours with complete resolution of the cardiac damage without complications. Based on the current literature, this is the first reported case of cardiotoxicity induced by an ophthalmic solution of tropicamide and phenylephrine used intramuscularly for voluntary purposes. https://www.pagepressjournals.org/index.php/ecj/article/view/11320tropicamidephenylephrinecardiotoxicityhypertensiontroponindrug-induced toxicity |
| spellingShingle | Antonio Agosti Andrea Vercelli Elena Demichele Francesco Mariani Andrea Biagi Stefano Ferraro Gianfranco Cervellin Erika Poggiali A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman Emergency Care Journal tropicamide phenylephrine cardiotoxicity hypertension troponin drug-induced toxicity |
| title | A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman |
| title_full | A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman |
| title_fullStr | A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman |
| title_full_unstemmed | A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman |
| title_short | A case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug-addicted young woman |
| title_sort | case of cardiotoxicity following intramuscular injection of tropicamide and phenylephrine ophthalmic solution in a drug addicted young woman |
| topic | tropicamide phenylephrine cardiotoxicity hypertension troponin drug-induced toxicity |
| url | https://www.pagepressjournals.org/index.php/ecj/article/view/11320 |
| work_keys_str_mv | AT antonioagosti acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT andreavercelli acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT elenademichele acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT francescomariani acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT andreabiagi acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT stefanoferraro acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT gianfrancocervellin acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT erikapoggiali acaseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT antonioagosti caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT andreavercelli caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT elenademichele caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT francescomariani caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT andreabiagi caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT stefanoferraro caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT gianfrancocervellin caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman AT erikapoggiali caseofcardiotoxicityfollowingintramuscularinjectionoftropicamideandphenylephrineophthalmicsolutioninadrugaddictedyoungwoman |