The sickle cell trait and end stage renal disease in Salvador, Brazil.

The sickle cell trait and end stage renal disease in Salvador, Brazil.

BACKGROUND:Carriers of the sickle cell trait (HbAS) usually remain asymptomatic. However, under conditions of low tissue oxygenation, red blood cell sickling and vascular obstruction may develop. Chronic kidney disease (CKD) can arise from conditions promoting low-oxygen in kidney tissue, which may...

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Main Authors: Dona J Alladagbin, Paula N Fernandes, Maria B Tavares, Jean T Brito, Geraldo G S Oliveira, Luciano K Silva, Nadia A Khouri, Marilia B Oliveira, Tatiana Amorim, Cácia M Matos, Guilherme S Ribeiro, Antônio A Lopes, Marilda S Gonçalves, Washington L C Dos-Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209036

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