H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis

H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis

Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) occurring on th...

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Bibliographic Details
Main Authors: Jialei Hu, Greg Donahue, Jean Dorsey, Jérôme Govin, Zuofei Yuan, Benjamin A. Garcia, Parisha P. Shah, Shelley L. Berger
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Subjects:
chromatin
histone
acetylation
sporulation
meiotic recombination
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715012590

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