Decrease in Mycophenolic Acid Plasma Level by Sacubitril/Valsartan in a Lupus Nephritis Patient: A Case Report

Decrease in Mycophenolic Acid Plasma Level by Sacubitril/Valsartan in a Lupus Nephritis Patient: A Case Report

Introduction: Mycophenolate mofetil (MMF), an inactive prodrug of mycophenolic acid (MPA), is an immunosuppressive drug used widely in the treatment of lupus nephritis. In this case report, the area under the blood concentration time curve (AUC) of MPA was significantly decreased by the concomitant...

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Bibliographic Details
Main Authors: Shunsuke Nashimoto, Masashi Miyamae, Issei Higuchi, Michihito Kono, Maria Tada, Tatsuya Atsumi, Mitsuru Sugawara, Yoh Takekuma
Format: Article
Language:English
Published: Karger Publishers 2024-02-01
Series:Case Reports in Nephrology and Dialysis
Subjects:
systemic lupus erythematosus
lupus nephritis
hypertension
pharmacokinetics
drug-drug interaction
Online Access:https://beta.karger.com/Article/FullText/536468

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