Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice

Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice

Elucidating the underlying molecular mechanisms regulating fear and extinction learning may offer insights that can lead to novel treatments for debilitating anxiety and trauma-related disorders including posttraumatic stress disorder. The endocannabinoid (eCB) system is a retrograde inhibitory sign...

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Bibliographic Details
Main Authors: Victoria S. Cavener, Andrew Gaulden, Dante Pennipede, Puja Jagasia, Jashim Uddin, Lawrence J. Marnett, Sachin Patel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neuroscience
Subjects:
FAAH
endocannabinoid
fear
stress
extinction
cannabinoid
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00479/full

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