miR-133a Promotes TRAIL Resistance in Glioblastoma via Suppressing Death Receptor 5 and Activating NF-κB Signaling

miR-133a Promotes TRAIL Resistance in Glioblastoma via Suppressing Death Receptor 5 and Activating NF-κB Signaling

Recombinant tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), as a novel cancer therapeutic, is being tested in phase II and III clinical trials; however, TRAIL resistance remains a big obstacle preventing its clinical application. Considering that TRAIL-induced apoptosis throug...

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Bibliographic Details
Main Authors: Shan-shan Wang, Lu Feng, Bao-guang Hu, Ying-fei Lu, Wei-mao Wang, Wei Guo, Chun-wai Suen, Bao-hua Jiao, Jian-xin Pang, Wei-ming Fu, Jin-fang Zhang
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117302263

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http://www.sciencedirect.com/science/article/pii/S2162253117302263

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