Absolute quantification of DNA damage response proteins

Absolute quantification of DNA damage response proteins

Abstract Background DNA damage response (DDR) and repair are vital for safeguarding genetic information and ensuring the survival and accurate transmission of genetic material. DNA damage, such as DNA double-strand breaks (DSBs), triggers a response where sensor proteins recognize DSBs. Information...

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Bibliographic Details
Main Authors: Shun Matsuda, Tsuyoshi Ikura, Tomonari Matsuda
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Genes and Environment
Subjects:
MDC1
γH2AX
Absolute quantification
LC-MS/MS
Chromatin affinity
DNA damage response
Online Access:https://doi.org/10.1186/s41021-023-00295-0

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