Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients

In the past, extrapulmonary tuberculosis affected approximately 70% of patients with advanced pulmonary tuberculosis. However, with the advent of highly effective therapy, intestinal tuberculosis has become rare ― even more unusual in patients without immunodeficiency, HIV and pulmonary di...

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Main Authors: Eduardo Brambilla, Marcos Dal Ponte, Leonardo Gilmone Ruschel, Pedro Guarise Da Silva
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2012-09-01
Series:Journal of Coloproctology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000300015
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author Eduardo Brambilla
Marcos Dal Ponte
Leonardo Gilmone Ruschel
Pedro Guarise Da Silva
author_facet Eduardo Brambilla
Marcos Dal Ponte
Leonardo Gilmone Ruschel
Pedro Guarise Da Silva
author_sort Eduardo Brambilla
collection DOAJ
description In the past, extrapulmonary tuberculosis affected approximately 70% of patients with advanced pulmonary tuberculosis. However, with the advent of highly effective therapy, intestinal tuberculosis has become rare &#8213; even more unusual in patients without immunodeficiency, HIV and pulmonary disease. The purpose of this study was to report the case of two patients diagnosed with intestinal tuberculosis and no immunodeficiency, HIV or lung disease. The first patient was diagnosed by colonoscopy performed in a mass located in the ileocecal region. After the tuberculosis treatment, the patient presented improvement regarding the mass and symptoms. The diagnosis of the second patient was achieved only with surgical resection of the lesion in proximal transverse colon. It is important for health professionals to know that intestinal tuberculosis should be considered as differential diagnosis of intestinal diseases, also for immunocompetent patients, even regarded as a rare disease.<br>No passado, a tuberculose extrapulmonar acometia cerca de 70% dos pacientes com tuberculose pulmonar avançada. Porém, com o surgimento da terapia de alta eficácia, a tuberculose intestinal tornou-se de ocorrência mais rara - sendo ainda mais incomum de ocorrer em pacientes sem imunodeficiência, HIV e doença pulmonar. O objetivo deste estudo foi apresentar o caso de dois pacientes diagnosticados com tuberculose intestinal, sem sinais de imunodeficiência, HIV ou doença pulmonar. A primeira paciente foi diagnosticada por meio de biópsias realizadas por colonoscopia em uma massa localizada em região ileocecal; após o tratamento da tuberculose a paciente apresentou melhora da lesão e dos sintomas. O diagnóstico do segundo paciente só foi obtido com a ressecção cirúrgica da lesão em cólon transverso proximal. É importante que os profissionais da saúde saibam que a tuberculose intestinal deve ser considerada como diagnóstico diferencial de patologias intestinais, até mesmo em pacientes imunocompetentes, mesmo sendo rara.
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spelling doaj.art-828d7e25073644468fecd27e9f5975e22022-12-21T22:05:03ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632012-09-01323304307Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patientsEduardo BrambillaMarcos Dal PonteLeonardo Gilmone RuschelPedro Guarise Da SilvaIn the past, extrapulmonary tuberculosis affected approximately 70% of patients with advanced pulmonary tuberculosis. However, with the advent of highly effective therapy, intestinal tuberculosis has become rare &#8213; even more unusual in patients without immunodeficiency, HIV and pulmonary disease. The purpose of this study was to report the case of two patients diagnosed with intestinal tuberculosis and no immunodeficiency, HIV or lung disease. The first patient was diagnosed by colonoscopy performed in a mass located in the ileocecal region. After the tuberculosis treatment, the patient presented improvement regarding the mass and symptoms. The diagnosis of the second patient was achieved only with surgical resection of the lesion in proximal transverse colon. It is important for health professionals to know that intestinal tuberculosis should be considered as differential diagnosis of intestinal diseases, also for immunocompetent patients, even regarded as a rare disease.<br>No passado, a tuberculose extrapulmonar acometia cerca de 70% dos pacientes com tuberculose pulmonar avançada. Porém, com o surgimento da terapia de alta eficácia, a tuberculose intestinal tornou-se de ocorrência mais rara - sendo ainda mais incomum de ocorrer em pacientes sem imunodeficiência, HIV e doença pulmonar. O objetivo deste estudo foi apresentar o caso de dois pacientes diagnosticados com tuberculose intestinal, sem sinais de imunodeficiência, HIV ou doença pulmonar. A primeira paciente foi diagnosticada por meio de biópsias realizadas por colonoscopia em uma massa localizada em região ileocecal; após o tratamento da tuberculose a paciente apresentou melhora da lesão e dos sintomas. O diagnóstico do segundo paciente só foi obtido com a ressecção cirúrgica da lesão em cólon transverso proximal. É importante que os profissionais da saúde saibam que a tuberculose intestinal deve ser considerada como diagnóstico diferencial de patologias intestinais, até mesmo em pacientes imunocompetentes, mesmo sendo rara.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000300015tuberculosetuberculose gastrointestinalestudos de casotuberculosistuberculosisgastrointestinalcase studies
spellingShingle Eduardo Brambilla
Marcos Dal Ponte
Leonardo Gilmone Ruschel
Pedro Guarise Da Silva
Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
Journal of Coloproctology
tuberculose
tuberculose gastrointestinal
estudos de caso
tuberculosis
tuberculosis
gastrointestinal
case studies
title Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
title_full Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
title_fullStr Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
title_full_unstemmed Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
title_short Intestinal tuberculosis in immunocompetent/HIV negative patients: case report of two patients
title_sort intestinal tuberculosis in immunocompetent hiv negative patients case report of two patients
topic tuberculose
tuberculose gastrointestinal
estudos de caso
tuberculosis
tuberculosis
gastrointestinal
case studies
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000300015
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AT marcosdalponte intestinaltuberculosisinimmunocompetenthivnegativepatientscasereportoftwopatients
AT leonardogilmoneruschel intestinaltuberculosisinimmunocompetenthivnegativepatientscasereportoftwopatients
AT pedroguarisedasilva intestinaltuberculosisinimmunocompetenthivnegativepatientscasereportoftwopatients