Amamistatins isolated from Nocardia altamirensis

Four new phenolic siderophores were isolated from the actinomycete Nocardia altamirensis along with the known natural product amamistatin B and a putative biosynthetic shunt product. The structures of all compounds were elucidated through 1D and 2D NMR analyses as well as mass spectrometry. The iron...

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Main Authors: Till Steinmetz, Wolf Hiller, Markus Nett
Format: Article
Language:English
Published: Beilstein-Institut 2022-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.18.40
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author Till Steinmetz
Wolf Hiller
Markus Nett
author_facet Till Steinmetz
Wolf Hiller
Markus Nett
author_sort Till Steinmetz
collection DOAJ
description Four new phenolic siderophores were isolated from the actinomycete Nocardia altamirensis along with the known natural product amamistatin B and a putative biosynthetic shunt product. The structures of all compounds were elucidated through 1D and 2D NMR analyses as well as mass spectrometry. The iron-chelating properties of the retrieved metabolites were evaluated in a chrome azurol S assay.
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spelling doaj.art-82908c9a8000455aa22b93abde4c092d2022-12-22T02:50:26ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972022-03-0118136036710.3762/bjoc.18.401860-5397-18-40Amamistatins isolated from Nocardia altamirensisTill Steinmetz0Wolf Hiller1Markus Nett2Department of Biochemical and Chemical Engineering, Laboratory of Technical Biology, TU Dortmund University, Emil-Figge-Strasse 66, 44227 Dortmund, GermanyDepartment of Chemistry and Chemical Biology, TU Dortmund University, GermanyDepartment of Biochemical and Chemical Engineering, Laboratory of Technical Biology, TU Dortmund University, Emil-Figge-Strasse 66, 44227 Dortmund, GermanyFour new phenolic siderophores were isolated from the actinomycete Nocardia altamirensis along with the known natural product amamistatin B and a putative biosynthetic shunt product. The structures of all compounds were elucidated through 1D and 2D NMR analyses as well as mass spectrometry. The iron-chelating properties of the retrieved metabolites were evaluated in a chrome azurol S assay.https://doi.org/10.3762/bjoc.18.40actinomyceteamamistatinnocardiasiderophorestructure elucidation
spellingShingle Till Steinmetz
Wolf Hiller
Markus Nett
Amamistatins isolated from Nocardia altamirensis
Beilstein Journal of Organic Chemistry
actinomycete
amamistatin
nocardia
siderophore
structure elucidation
title Amamistatins isolated from Nocardia altamirensis
title_full Amamistatins isolated from Nocardia altamirensis
title_fullStr Amamistatins isolated from Nocardia altamirensis
title_full_unstemmed Amamistatins isolated from Nocardia altamirensis
title_short Amamistatins isolated from Nocardia altamirensis
title_sort amamistatins isolated from nocardia altamirensis
topic actinomycete
amamistatin
nocardia
siderophore
structure elucidation
url https://doi.org/10.3762/bjoc.18.40
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