Oral Administration of Resveratrol-Loaded Solid Lipid Nanoparticle Improves Insulin Resistance Through Targeting Expression of SNARE Proteins in Adipose and Muscle Tissue in Rats with Type 2 Diabetes

Oral Administration of Resveratrol-Loaded Solid Lipid Nanoparticle Improves Insulin Resistance Through Targeting Expression of SNARE Proteins in Adipose and Muscle Tissue in Rats with Type 2 Diabetes

Abstract In the current study, we developed resveratrol (RES)-loaded solid lipid nanoparticle (SLN-RES) in order to improve insulin resistance through the upregulation of SNARE protein complex in rats with type 2 diabetes. The SLN-RES characteristics include the following: the average size of 248 nm...

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Bibliographic Details
Main Authors: Roohollah Mohseni, Zahra ArabSadeghabadi, Nasrin Ziamajidi, Roghayeh Abbasalipourkabir, Azam RezaeiFarimani
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:Nanoscale Research Letters
Subjects:
Nanoparticles
Resveratrol
Insulin resistance
SNARE proteins
Online Access:http://link.springer.com/article/10.1186/s11671-019-3042-7

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