Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-γ-Induced Gene Expression

Tryptophanyl-Transfer RNA Synthetase Is Involved in a Negative Feedback Loop Mitigating Interferon-γ-Induced Gene Expression

Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes responsible for linking a transfer RNA (tRNA) with its cognate amino acid present in all the kingdoms of life. Besides their aminoacyl-tRNA synthetase activity, it was described that many of these enzymes can carry out non-canonical functions....

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Bibliographic Details
Main Authors: Ikrame Lazar, Ido Livneh, Aaron Ciechanover, Bertrand Fabre
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
tryptophanyl-tRNA synthetase
melanoma
interferon-γ
signal transducer and activator of transcription 1
proteomics
mass spectrometry
Online Access:https://www.mdpi.com/2073-4409/13/2/180

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