Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims
Helen Hahn,1 Tzy-Chyi Yu,1 Chia-Chen Teng,2 Hiangkiat Tan2 1Mallinckrodt Pharmaceuticals, Hampton, NJ, USA; 2Healthcore, Inc., Wilmington, DE, USACorrespondence: Tzy-Chyi Yu, Mallinckrodt Pharmaceuticals, Shelbourne Building, 53 Frontage Road, Suite 300, Hampton, NJ, 08827, USA, Tel +1 908 238 6884,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-04-01
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| Series: | ClinicoEconomics and Outcomes Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/holistic-view-of-autografting-patients-by-percentage-of-total-body-sur-peer-reviewed-fulltext-article-CEOR |
| _version_ | 1797848451685285888 |
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| author | Hahn H Yu TC Teng CC Tan H |
| author_facet | Hahn H Yu TC Teng CC Tan H |
| author_sort | Hahn H |
| collection | DOAJ |
| description | Helen Hahn,1 Tzy-Chyi Yu,1 Chia-Chen Teng,2 Hiangkiat Tan2 1Mallinckrodt Pharmaceuticals, Hampton, NJ, USA; 2Healthcore, Inc., Wilmington, DE, USACorrespondence: Tzy-Chyi Yu, Mallinckrodt Pharmaceuticals, Shelbourne Building, 53 Frontage Road, Suite 300, Hampton, NJ, 08827, USA, Tel +1 908 238 6884, Email amanda.yu@mnk.comAim: This retrospective observational study provides a holistic view of the clinical and economic characteristics of inpatient treatment of patients with thermal burns undergoing autografting, by integrating real-world data (RWD) from medical records from healthcare providers (HCPs) and administrative claims.Methods: We identified eligible patients between July 1, 2010, and November 30, 2019, from the HealthCore Integrated Research Database® (HIRD®) and obtained their medical records from HCPs. We abstracted data from medical records to describe patient demographics and clinical characteristics and obtained costs of treatment from claims.Results: Two hundred patients were stratified into cohorts based on the percentage of total body surface area (%TBSA) burned: minor (< 10%), moderate (10%– 24%), and major (≥ 25%). Data obtained from medical records and administrative claims were comparable to previous findings from administrative claims data. This privately insured study cohort predominantly consisted of White men. Diabetes mellitus and hypertension were frequently reported in a relatively young population. Key clinical characteristics that could influence burn treatment decisions and long-term outcomes, such as body mass index, size of autograft donor site, and mesh ratio, were frequently underdocumented in patients’ medical records.Conclusion: Evidence generated from 2 orthogonal RWD sources confirmed that patients with larger %TBSA burned required more intensive care, thereby incurring higher costs. This study highlights considerable incompleteness in many critical fields in medical records, which limits the ability to generate broader insights. More comprehensive documentation of clinical characteristics and outcomes of autografts and donor sites in the operative and medical notes is critical to appropriately evaluate their impact on outcomes of burn treatments in future research using RWD.Keywords: burn injury, healthcare resource utilization, treatment patterns, real-world data |
| first_indexed | 2024-04-09T18:28:49Z |
| format | Article |
| id | doaj.art-8295dac0b4854739af8dd670ff784b43 |
| institution | Directory Open Access Journal |
| issn | 1178-6981 |
| language | English |
| last_indexed | 2024-04-09T18:28:49Z |
| publishDate | 2023-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | ClinicoEconomics and Outcomes Research |
| spelling | doaj.art-8295dac0b4854739af8dd670ff784b432023-04-11T19:04:59ZengDove Medical PressClinicoEconomics and Outcomes Research1178-69812023-04-01Volume 1525126782917Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative ClaimsHahn HYu TCTeng CCTan HHelen Hahn,1 Tzy-Chyi Yu,1 Chia-Chen Teng,2 Hiangkiat Tan2 1Mallinckrodt Pharmaceuticals, Hampton, NJ, USA; 2Healthcore, Inc., Wilmington, DE, USACorrespondence: Tzy-Chyi Yu, Mallinckrodt Pharmaceuticals, Shelbourne Building, 53 Frontage Road, Suite 300, Hampton, NJ, 08827, USA, Tel +1 908 238 6884, Email amanda.yu@mnk.comAim: This retrospective observational study provides a holistic view of the clinical and economic characteristics of inpatient treatment of patients with thermal burns undergoing autografting, by integrating real-world data (RWD) from medical records from healthcare providers (HCPs) and administrative claims.Methods: We identified eligible patients between July 1, 2010, and November 30, 2019, from the HealthCore Integrated Research Database® (HIRD®) and obtained their medical records from HCPs. We abstracted data from medical records to describe patient demographics and clinical characteristics and obtained costs of treatment from claims.Results: Two hundred patients were stratified into cohorts based on the percentage of total body surface area (%TBSA) burned: minor (< 10%), moderate (10%– 24%), and major (≥ 25%). Data obtained from medical records and administrative claims were comparable to previous findings from administrative claims data. This privately insured study cohort predominantly consisted of White men. Diabetes mellitus and hypertension were frequently reported in a relatively young population. Key clinical characteristics that could influence burn treatment decisions and long-term outcomes, such as body mass index, size of autograft donor site, and mesh ratio, were frequently underdocumented in patients’ medical records.Conclusion: Evidence generated from 2 orthogonal RWD sources confirmed that patients with larger %TBSA burned required more intensive care, thereby incurring higher costs. This study highlights considerable incompleteness in many critical fields in medical records, which limits the ability to generate broader insights. More comprehensive documentation of clinical characteristics and outcomes of autografts and donor sites in the operative and medical notes is critical to appropriately evaluate their impact on outcomes of burn treatments in future research using RWD.Keywords: burn injury, healthcare resource utilization, treatment patterns, real-world datahttps://www.dovepress.com/holistic-view-of-autografting-patients-by-percentage-of-total-body-sur-peer-reviewed-fulltext-article-CEORburn injuryhealthcare resource utilizationtreatment patternsreal-world data |
| spellingShingle | Hahn H Yu TC Teng CC Tan H Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims ClinicoEconomics and Outcomes Research burn injury healthcare resource utilization treatment patterns real-world data |
| title | Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims |
| title_full | Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims |
| title_fullStr | Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims |
| title_full_unstemmed | Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims |
| title_short | Holistic View of Autografting Patients by Percentage of Total Body Surface Area Burned: Medical Record Abstraction Integrated with Administrative Claims |
| title_sort | holistic view of autografting patients by percentage of total body surface area burned medical record abstraction integrated with administrative claims |
| topic | burn injury healthcare resource utilization treatment patterns real-world data |
| url | https://www.dovepress.com/holistic-view-of-autografting-patients-by-percentage-of-total-body-sur-peer-reviewed-fulltext-article-CEOR |
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