Influence of a Physiologically Formed Blood Clot on Pre-Osteoblastic Cells Grown on a BMP-7-Coated Nanoporous Titanium Surface

Influence of a Physiologically Formed Blood Clot on Pre-Osteoblastic Cells Grown on a BMP-7-Coated Nanoporous Titanium Surface

Titanium (Ti) nanotopography modulates the osteogenic response to exogenous bone morphogenetic protein 7 (BMP-7) in vitro, supporting enhanced alkaline phosphatase mRNA expression and activity, as well as higher osteopontin (OPN) mRNA and protein levels. As the biological effects of OPN protein are...

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Bibliographic Details
Main Authors: Leonardo Raphael Zuardi, Cleide Lúcia Araújo Silva, Eduardo Magalhães Rego, Giovana Vacilotto Carneiro, Silvia Spriano, Antonio Nanci, Paulo Tambasco de Oliveira
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomimetics
Subjects:
BMP-7
osteoblast
titanium
nanotopography
blood clot
Online Access:https://www.mdpi.com/2313-7673/8/1/123

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