In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum

The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about  484.7 kDa. Monosaccharide analysis revealed that DDP was co...

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Main Authors: XingJin He, Yijun Fan, Aoshuang Luo, Aoxue Luo, Ze Chun, Zhongfu Ge
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/2/1579/
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author XingJin He
Yijun Fan
Aoshuang Luo
Aoxue Luo
Ze Chun
Zhongfu Ge
author_facet XingJin He
Yijun Fan
Aoshuang Luo
Aoxue Luo
Ze Chun
Zhongfu Ge
author_sort XingJin He
collection DOAJ
description The water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about  484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant.
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spelling doaj.art-82996ee6dd9a409b823135aae94b16e82022-12-22T02:46:46ZengMDPI AGMolecules1420-30492011-02-011621579159210.3390/molecules16021579In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanumXingJin HeYijun FanAoshuang LuoAoxue LuoZe ChunZhongfu GeThe water-soluble crude polysaccharide (DDP) obtained from the aqueous extracts of the stem of Dendrobium denneanum through hot water extraction followed by ethanol precipitation, was found to have an average molecular weight (Mw) of about  484.7 kDa. Monosaccharide analysis revealed that DDP was composed of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 1.00:2.66:8.92:34.20:10.16. The investigation of antioxidant activity both in vitro and in vivo showed that DDP is a potential antioxidant.http://www.mdpi.com/1420-3049/16/2/1579/Dendrobium denneanumpolysaccharideantioxidant activity
spellingShingle XingJin He
Yijun Fan
Aoshuang Luo
Aoxue Luo
Ze Chun
Zhongfu Ge
In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
Molecules
Dendrobium denneanum
polysaccharide
antioxidant activity
title In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_full In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_fullStr In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_full_unstemmed In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_short In Vitro and In Vivo Antioxidant Activity of a Water-Soluble Polysaccharide from Dendrobium denneanum
title_sort in vitro and in vivo antioxidant activity of a water soluble polysaccharide from dendrobium denneanum
topic Dendrobium denneanum
polysaccharide
antioxidant activity
url http://www.mdpi.com/1420-3049/16/2/1579/
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