Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study
Acute heart failure (AHF) may lead to subclinical tissue ischemia due to hypoperfusion from inadequate forward flow or congestion. The aim of the present study is to test whether lactate levels are elevated in emergency department (ED) patients with AHF. A prospective pilot study of ED AHF patients...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2016-04-01
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| Series: | Emergency Care Journal |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/ecj/article/view/5458 |
| _version_ | 1818040016524279808 |
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| author | Kori Sauser Lora Alkhawam Linda Pierchala Peter S. Pang |
| author_facet | Kori Sauser Lora Alkhawam Linda Pierchala Peter S. Pang |
| author_sort | Kori Sauser |
| collection | DOAJ |
| description | Acute heart failure (AHF) may lead to subclinical tissue ischemia due to hypoperfusion from inadequate forward flow or congestion. The aim of the present study is to test whether lactate levels are elevated in emergency department (ED) patients with AHF. A prospective pilot study of ED AHF patients was conducted. Venous lactate level was measured at baseline and 6-12 hours after initial draw. Of the 50 patients enrolled, mean age was 65.3 years, 68% were male. Only 7 (14%) had an elevated lactate on either draw, with no differences in baseline characteristics between patients with and without elevated lactate. Patients with an elevated lactate had a higher mean heart rate (99 <em>vs</em> 81, P=0.03) and trended toward an increased rate of abnormal initial temperature (57 <em>vs</em> 23%, P=0.06). In this pilot study, only a minority of acute HF patients had an elevated lactate on presentation. |
| first_indexed | 2024-12-10T08:07:49Z |
| format | Article |
| id | doaj.art-8299be6cc3204f4c922c7482609ea8b9 |
| institution | Directory Open Access Journal |
| issn | 1826-9826 2282-2054 |
| language | English |
| last_indexed | 2024-12-10T08:07:49Z |
| publishDate | 2016-04-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Emergency Care Journal |
| spelling | doaj.art-8299be6cc3204f4c922c7482609ea8b92022-12-22T01:56:38ZengPAGEPress PublicationsEmergency Care Journal1826-98262282-20542016-04-011110.4081/ecj.2016.54584707Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot studyKori Sauser0Lora Alkhawam1Linda Pierchala2Peter S. Pang3Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MADepartment of Emergency Medicine, Northwestern University, Feinberg School of Medicine, Chicago, ILLoyola University Medical Center, Chicago, ILDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, INAcute heart failure (AHF) may lead to subclinical tissue ischemia due to hypoperfusion from inadequate forward flow or congestion. The aim of the present study is to test whether lactate levels are elevated in emergency department (ED) patients with AHF. A prospective pilot study of ED AHF patients was conducted. Venous lactate level was measured at baseline and 6-12 hours after initial draw. Of the 50 patients enrolled, mean age was 65.3 years, 68% were male. Only 7 (14%) had an elevated lactate on either draw, with no differences in baseline characteristics between patients with and without elevated lactate. Patients with an elevated lactate had a higher mean heart rate (99 <em>vs</em> 81, P=0.03) and trended toward an increased rate of abnormal initial temperature (57 <em>vs</em> 23%, P=0.06). In this pilot study, only a minority of acute HF patients had an elevated lactate on presentation.http://www.pagepressjournals.org/index.php/ecj/article/view/5458Acute heart failureLactateEmergency departmentHypoperfusion |
| spellingShingle | Kori Sauser Lora Alkhawam Linda Pierchala Peter S. Pang Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study Emergency Care Journal Acute heart failure Lactate Emergency department Hypoperfusion |
| title | Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study |
| title_full | Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study |
| title_fullStr | Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study |
| title_full_unstemmed | Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study |
| title_short | Lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department: a pilot study |
| title_sort | lactate levels as a marker of tissue hypoperfusion in acute heart failure patients seen in the emergency department a pilot study |
| topic | Acute heart failure Lactate Emergency department Hypoperfusion |
| url | http://www.pagepressjournals.org/index.php/ecj/article/view/5458 |
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