A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 monoclonal antibody), and hetrombopag. The coexistence...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
2024-02-01
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| Series: | Shanghai Jiaotong Daxue xuebao. Yixue ban |
| Subjects: | |
| Online Access: | https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.016 |
| _version_ | 1797244987892563968 |
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| author | LIU Jiayu HUANG Fang HAO Siguo |
| author_facet | LIU Jiayu HUANG Fang HAO Siguo |
| author_sort | LIU Jiayu |
| collection | DOAJ |
| description | Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 monoclonal antibody), and hetrombopag. The coexistence mechanism of CMML and ITP needs to be further clarified. Venetoclax combined with anti-CD20 monoclonal antibody and thrombopoietin receptor agonist may be an effective strategy for the treatment of this complication. |
| first_indexed | 2024-04-24T19:19:45Z |
| format | Article |
| id | doaj.art-829ffb7ccd52476794eb67607adbf3bd |
| institution | Directory Open Access Journal |
| issn | 1674-8115 |
| language | zho |
| last_indexed | 2024-04-24T19:19:45Z |
| publishDate | 2024-02-01 |
| publisher | Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) |
| record_format | Article |
| series | Shanghai Jiaotong Daxue xuebao. Yixue ban |
| spelling | doaj.art-829ffb7ccd52476794eb67607adbf3bd2024-03-26T03:15:47ZzhoEditorial Office of Journal of Shanghai Jiao Tong University (Medical Science)Shanghai Jiaotong Daxue xuebao. Yixue ban1674-81152024-02-0144228729010.3969/j.issn.1674-8115.2024.02.0161674-8115（2024）02-0287-04A case of chronic myelomonocytic leukemia complicated with immune thrombocytopeniaLIU JiayuHUANG FangHAO SiguoChronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 monoclonal antibody), and hetrombopag. The coexistence mechanism of CMML and ITP needs to be further clarified. Venetoclax combined with anti-CD20 monoclonal antibody and thrombopoietin receptor agonist may be an effective strategy for the treatment of this complication.https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.016chronic myelomonocytic leukemiaimmune thrombocytopeniavenetoclaxhetrombopagripertamab |
| spellingShingle | LIU Jiayu HUANG Fang HAO Siguo A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia Shanghai Jiaotong Daxue xuebao. Yixue ban chronic myelomonocytic leukemia immune thrombocytopenia venetoclax hetrombopag ripertamab |
| title | A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| title_full | A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| title_fullStr | A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| title_full_unstemmed | A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| title_short | A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| title_sort | case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia |
| topic | chronic myelomonocytic leukemia immune thrombocytopenia venetoclax hetrombopag ripertamab |
| url | https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2024.02.016 |
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