Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease
Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent...
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| Format: | Article |
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MDPI AG
2023-04-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/5/1086 |
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| author | Elisabetta Tonet Alberto Boccadoro Marco Micillo Marta Cocco Alberto Cossu Graziella Pompei Melchiore Giganti Gianluca Campo |
| author_facet | Elisabetta Tonet Alberto Boccadoro Marco Micillo Marta Cocco Alberto Cossu Graziella Pompei Melchiore Giganti Gianluca Campo |
| author_sort | Elisabetta Tonet |
| collection | DOAJ |
| description | Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent technologic developments in CCTA provide additional relevant information that can be considered as “novel markers” for risk stratification in different settings, including ischemic heart disease, atrial fibrillation, and myocardial inflammation. These markers include: (i) epicardial adipose tissue (EAT), associated with plaque development and the occurrence of arrhythmias; (ii) late iodine enhancement (LIE), which allows the identification of myocardial fibrosis; and (iii) plaque characterization, which provides data about plaque vulnerability. In the precision medicine era, these emerging markers should be integrated into CCTA evaluation to allow for the bespoke interventional and pharmacological management of each patient. |
| first_indexed | 2024-03-11T03:34:32Z |
| format | Article |
| id | doaj.art-82ad976877b74dbe8d417093bf7a757d |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T03:34:32Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-82ad976877b74dbe8d417093bf7a757d2023-11-18T02:08:27ZengMDPI AGLife2075-17292023-04-01135108610.3390/life13051086Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery DiseaseElisabetta Tonet0Alberto Boccadoro1Marco Micillo2Marta Cocco3Alberto Cossu4Graziella Pompei5Melchiore Giganti6Gianluca Campo7Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyDepartment of Morphology, Surgery and Experimental Medicine, Section of Radiology, University of Ferrara, 44121 Ferrara, ItalyCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyDepartment of Morphology, Surgery and Experimental Medicine, Section of Radiology, University of Ferrara, 44121 Ferrara, ItalyCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Cona, ItalyNowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent technologic developments in CCTA provide additional relevant information that can be considered as “novel markers” for risk stratification in different settings, including ischemic heart disease, atrial fibrillation, and myocardial inflammation. These markers include: (i) epicardial adipose tissue (EAT), associated with plaque development and the occurrence of arrhythmias; (ii) late iodine enhancement (LIE), which allows the identification of myocardial fibrosis; and (iii) plaque characterization, which provides data about plaque vulnerability. In the precision medicine era, these emerging markers should be integrated into CCTA evaluation to allow for the bespoke interventional and pharmacological management of each patient.https://www.mdpi.com/2075-1729/13/5/1086coronary CTAepicardial fatplaque featureslate iodine enhancement |
| spellingShingle | Elisabetta Tonet Alberto Boccadoro Marco Micillo Marta Cocco Alberto Cossu Graziella Pompei Melchiore Giganti Gianluca Campo Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease Life coronary CTA epicardial fat plaque features late iodine enhancement |
| title | Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease |
| title_full | Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease |
| title_fullStr | Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease |
| title_full_unstemmed | Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease |
| title_short | Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease |
| title_sort | coronary computed tomography angiography beyond obstructive coronary artery disease |
| topic | coronary CTA epicardial fat plaque features late iodine enhancement |
| url | https://www.mdpi.com/2075-1729/13/5/1086 |
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