Irisin: A bridge between exercise and neurological diseases
Exercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Elsevier
2022-12-01
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Series: | Heliyon |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022036404 |
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author | Yingjin Zhang Xuchang Zhang Shijun Lin |
author_facet | Yingjin Zhang Xuchang Zhang Shijun Lin |
author_sort | Yingjin Zhang |
collection | DOAJ |
description | Exercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing a protective role in multiple human organs. The protective effect of irisin on the nervous system is particularly remarkable, which can improve cognitive function, reduce the risk of ischemic stroke and improve its prognosis. Irisin also plays a guiding role in the prevention and treatment of neurodegenerative diseases and ischemic cerebrovascular diseases. Exercise is the driving factor promoting irisin secretion, and different exercise modes, intensity, frequency, and time all affect the level of serum irisin. As a result of analyzing the effects of various exercise modes on irisin secretion, we proposed an exercise program with a higher level of irisin secretion. |
first_indexed | 2024-04-11T00:51:15Z |
format | Article |
id | doaj.art-82af38870dc84c39a7731c616d0120ef |
institution | Directory Open Access Journal |
issn | 2405-8440 |
language | English |
last_indexed | 2024-04-11T00:51:15Z |
publishDate | 2022-12-01 |
publisher | Elsevier |
record_format | Article |
series | Heliyon |
spelling | doaj.art-82af38870dc84c39a7731c616d0120ef2023-01-05T08:40:03ZengElsevierHeliyon2405-84402022-12-01812e12352Irisin: A bridge between exercise and neurological diseasesYingjin Zhang0Xuchang Zhang1Shijun Lin2Geriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaGeriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaCorresponding author.; Geriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaExercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing a protective role in multiple human organs. The protective effect of irisin on the nervous system is particularly remarkable, which can improve cognitive function, reduce the risk of ischemic stroke and improve its prognosis. Irisin also plays a guiding role in the prevention and treatment of neurodegenerative diseases and ischemic cerebrovascular diseases. Exercise is the driving factor promoting irisin secretion, and different exercise modes, intensity, frequency, and time all affect the level of serum irisin. As a result of analyzing the effects of various exercise modes on irisin secretion, we proposed an exercise program with a higher level of irisin secretion.http://www.sciencedirect.com/science/article/pii/S2405844022036404IrisinExerciseNeurological diseases |
spellingShingle | Yingjin Zhang Xuchang Zhang Shijun Lin Irisin: A bridge between exercise and neurological diseases Heliyon Irisin Exercise Neurological diseases |
title | Irisin: A bridge between exercise and neurological diseases |
title_full | Irisin: A bridge between exercise and neurological diseases |
title_fullStr | Irisin: A bridge between exercise and neurological diseases |
title_full_unstemmed | Irisin: A bridge between exercise and neurological diseases |
title_short | Irisin: A bridge between exercise and neurological diseases |
title_sort | irisin a bridge between exercise and neurological diseases |
topic | Irisin Exercise Neurological diseases |
url | http://www.sciencedirect.com/science/article/pii/S2405844022036404 |
work_keys_str_mv | AT yingjinzhang irisinabridgebetweenexerciseandneurologicaldiseases AT xuchangzhang irisinabridgebetweenexerciseandneurologicaldiseases AT shijunlin irisinabridgebetweenexerciseandneurologicaldiseases |