Irisin: A bridge between exercise and neurological diseases

Exercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing...

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Main Authors: Yingjin Zhang, Xuchang Zhang, Shijun Lin
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022036404
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author Yingjin Zhang
Xuchang Zhang
Shijun Lin
author_facet Yingjin Zhang
Xuchang Zhang
Shijun Lin
author_sort Yingjin Zhang
collection DOAJ
description Exercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing a protective role in multiple human organs. The protective effect of irisin on the nervous system is particularly remarkable, which can improve cognitive function, reduce the risk of ischemic stroke and improve its prognosis. Irisin also plays a guiding role in the prevention and treatment of neurodegenerative diseases and ischemic cerebrovascular diseases. Exercise is the driving factor promoting irisin secretion, and different exercise modes, intensity, frequency, and time all affect the level of serum irisin. As a result of analyzing the effects of various exercise modes on irisin secretion, we proposed an exercise program with a higher level of irisin secretion.
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spelling doaj.art-82af38870dc84c39a7731c616d0120ef2023-01-05T08:40:03ZengElsevierHeliyon2405-84402022-12-01812e12352Irisin: A bridge between exercise and neurological diseasesYingjin Zhang0Xuchang Zhang1Shijun Lin2Geriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaGeriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaCorresponding author.; Geriatrics Department, Longgang District People’s Hospital of Shenzhen, No.53 Aixin Rd, Shenzhen 518172, ChinaExercise plays a beneficial regulating role on each organ of the body through different mechanisms and is a powerful weapon to prevent disease. Irisin is released from muscle and widely distributed in the human body, participating in the physiological processes of multiple human systems and playing a protective role in multiple human organs. The protective effect of irisin on the nervous system is particularly remarkable, which can improve cognitive function, reduce the risk of ischemic stroke and improve its prognosis. Irisin also plays a guiding role in the prevention and treatment of neurodegenerative diseases and ischemic cerebrovascular diseases. Exercise is the driving factor promoting irisin secretion, and different exercise modes, intensity, frequency, and time all affect the level of serum irisin. As a result of analyzing the effects of various exercise modes on irisin secretion, we proposed an exercise program with a higher level of irisin secretion.http://www.sciencedirect.com/science/article/pii/S2405844022036404IrisinExerciseNeurological diseases
spellingShingle Yingjin Zhang
Xuchang Zhang
Shijun Lin
Irisin: A bridge between exercise and neurological diseases
Heliyon
Irisin
Exercise
Neurological diseases
title Irisin: A bridge between exercise and neurological diseases
title_full Irisin: A bridge between exercise and neurological diseases
title_fullStr Irisin: A bridge between exercise and neurological diseases
title_full_unstemmed Irisin: A bridge between exercise and neurological diseases
title_short Irisin: A bridge between exercise and neurological diseases
title_sort irisin a bridge between exercise and neurological diseases
topic Irisin
Exercise
Neurological diseases
url http://www.sciencedirect.com/science/article/pii/S2405844022036404
work_keys_str_mv AT yingjinzhang irisinabridgebetweenexerciseandneurologicaldiseases
AT xuchangzhang irisinabridgebetweenexerciseandneurologicaldiseases
AT shijunlin irisinabridgebetweenexerciseandneurologicaldiseases