Primary non-adherence to inhaled medications measured with e-prescription data from Poland

Abstract Background Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in ast...

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Main Authors: Grzegorz Kardas, Michał Panek, Piotr Kuna, Przemysław Kardas
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Clinical and Translational Allergy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13601-020-00346-7
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author Grzegorz Kardas
Michał Panek
Piotr Kuna
Przemysław Kardas
author_facet Grzegorz Kardas
Michał Panek
Piotr Kuna
Przemysław Kardas
author_sort Grzegorz Kardas
collection DOAJ
description Abstract Background Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in asthma and COPD emerged. The aim was to study primary non-adherence to inhaled medications available in Poland indicated in asthma and/or COPD and analyse the impact of patients’ demographics and inhalers’ characteristics (dry powder inhalers (DPIs) vs metered dose inhalers (MDIs) and presence of a dosage counter) on primary non-adherence. Methods A retrospective analysis of all e-prescriptions issued in Poland in 2018 (n = 119,880) from the national e-prescription pilot framework. Results Primary non-adherence for inhalable medications reached 15.3%. It significantly differed among age groups—the lowest (10.8%) was in 75 + years-old patients, highest (18%) in 65–74 years-old patients. No gender differences in primary non-adherence were found. The highest non-adherence was observed for ICS + LABA combinations (18.86%). A significant difference was found between MDI and DPI inhalers and between inhalers with/without a dosage counter. Conclusions Out of e-prescriptions for inhaled medications issued in 2018 in Poland, 15.3% were not redeemed. The degree of primary non-adherence was influenced by age, but not gender. Significant differences between MDIs and DPIs and between inhalers with/without a dosage counter were observed.
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spelling doaj.art-82b36cd196ca4094b68dc8229b169b1f2022-12-21T18:40:35ZengWileyClinical and Translational Allergy2045-70222020-10-011011810.1186/s13601-020-00346-7Primary non-adherence to inhaled medications measured with e-prescription data from PolandGrzegorz Kardas0Michał Panek1Piotr Kuna2Przemysław Kardas3Department of Internal Medicine, Asthma and Allergy, Medical University of LodzDepartment of Internal Medicine, Asthma and Allergy, Medical University of LodzDepartment of Internal Medicine, Asthma and Allergy, Medical University of LodzFirst Department of Family Medicine, Medical University of LodzAbstract Background Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique opportunities for studying primary non-adherence in asthma and COPD emerged. The aim was to study primary non-adherence to inhaled medications available in Poland indicated in asthma and/or COPD and analyse the impact of patients’ demographics and inhalers’ characteristics (dry powder inhalers (DPIs) vs metered dose inhalers (MDIs) and presence of a dosage counter) on primary non-adherence. Methods A retrospective analysis of all e-prescriptions issued in Poland in 2018 (n = 119,880) from the national e-prescription pilot framework. Results Primary non-adherence for inhalable medications reached 15.3%. It significantly differed among age groups—the lowest (10.8%) was in 75 + years-old patients, highest (18%) in 65–74 years-old patients. No gender differences in primary non-adherence were found. The highest non-adherence was observed for ICS + LABA combinations (18.86%). A significant difference was found between MDI and DPI inhalers and between inhalers with/without a dosage counter. Conclusions Out of e-prescriptions for inhaled medications issued in 2018 in Poland, 15.3% were not redeemed. The degree of primary non-adherence was influenced by age, but not gender. Significant differences between MDIs and DPIs and between inhalers with/without a dosage counter were observed.http://link.springer.com/article/10.1186/s13601-020-00346-7Inhaled medicationsInhalatorsAsthma adherenceCOPD adherencePrimary non-adherencee-prescription
spellingShingle Grzegorz Kardas
Michał Panek
Piotr Kuna
Przemysław Kardas
Primary non-adherence to inhaled medications measured with e-prescription data from Poland
Clinical and Translational Allergy
Inhaled medications
Inhalators
Asthma adherence
COPD adherence
Primary non-adherence
e-prescription
title Primary non-adherence to inhaled medications measured with e-prescription data from Poland
title_full Primary non-adherence to inhaled medications measured with e-prescription data from Poland
title_fullStr Primary non-adherence to inhaled medications measured with e-prescription data from Poland
title_full_unstemmed Primary non-adherence to inhaled medications measured with e-prescription data from Poland
title_short Primary non-adherence to inhaled medications measured with e-prescription data from Poland
title_sort primary non adherence to inhaled medications measured with e prescription data from poland
topic Inhaled medications
Inhalators
Asthma adherence
COPD adherence
Primary non-adherence
e-prescription
url http://link.springer.com/article/10.1186/s13601-020-00346-7
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