CSL controls telomere maintenance and genome stability in human dermal fibroblasts
Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important role in keratinocyte tumour development. Here the authors reveal that CSL plays a role in maintenance of telomeres and genomic integrity in both dermal fibroblasts and CAFs.
Main Authors: | Giulia Bottoni, Atul Katarkar, Beatrice Tassone, Soumitra Ghosh, Andrea Clocchiatti, Sandro Goruppi, Pino Bordignon, Paris Jafari, Fabio Tordini, Thomas Lunardi, Wolfram Hoetzenecker, Victor Neel, Joachim Lingner, G. Paolo Dotto |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-11785-7 |
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