Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy
Surface-enhanced Raman spectroscopy (SERS) merges nanotechnology with conventional Raman spectroscopy to produce an ultrasensitive and highly specific analytical tool that has been exploited as the optical signal read-out in a variety of advanced applications. In this feature article, we delineate t...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/11/7/230 |
_version_ | 1797527539688669184 |
---|---|
author | Irene Calderon Luca Guerrini Ramon A. Alvarez-Puebla |
author_facet | Irene Calderon Luca Guerrini Ramon A. Alvarez-Puebla |
author_sort | Irene Calderon |
collection | DOAJ |
description | Surface-enhanced Raman spectroscopy (SERS) merges nanotechnology with conventional Raman spectroscopy to produce an ultrasensitive and highly specific analytical tool that has been exploited as the optical signal read-out in a variety of advanced applications. In this feature article, we delineate the main features of the intertwined relationship between SERS and nucleic acids (NAs). In particular, we report representative examples of the implementation of SERS in biosensing platforms for NA detection, the integration of DNA as the biorecognition element onto plasmonic materials for SERS analysis of different classes of analytes (from metal ions to microorgniasms) and, finally, the use of structural DNA nanotechnology for the precise engineering of SERS-active nanomaterials. |
first_indexed | 2024-03-10T09:45:07Z |
format | Article |
id | doaj.art-82b8da978f7a4307baebfc35e89350bd |
institution | Directory Open Access Journal |
issn | 2079-6374 |
language | English |
last_indexed | 2024-03-10T09:45:07Z |
publishDate | 2021-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Biosensors |
spelling | doaj.art-82b8da978f7a4307baebfc35e89350bd2023-11-22T03:19:55ZengMDPI AGBiosensors2079-63742021-07-0111723010.3390/bios11070230Targets and Tools: Nucleic Acids for Surface-Enhanced Raman SpectroscopyIrene Calderon0Luca Guerrini1Ramon A. Alvarez-Puebla2Department of Physical and Inorganic Chemistry, Universitat Rovira i Virgili, Carrer de Marcel∙lí Domingo, s/n, 43007 Tarragona, SpainDepartment of Physical and Inorganic Chemistry, Universitat Rovira i Virgili, Carrer de Marcel∙lí Domingo, s/n, 43007 Tarragona, SpainDepartment of Physical and Inorganic Chemistry, Universitat Rovira i Virgili, Carrer de Marcel∙lí Domingo, s/n, 43007 Tarragona, SpainSurface-enhanced Raman spectroscopy (SERS) merges nanotechnology with conventional Raman spectroscopy to produce an ultrasensitive and highly specific analytical tool that has been exploited as the optical signal read-out in a variety of advanced applications. In this feature article, we delineate the main features of the intertwined relationship between SERS and nucleic acids (NAs). In particular, we report representative examples of the implementation of SERS in biosensing platforms for NA detection, the integration of DNA as the biorecognition element onto plasmonic materials for SERS analysis of different classes of analytes (from metal ions to microorgniasms) and, finally, the use of structural DNA nanotechnology for the precise engineering of SERS-active nanomaterials.https://www.mdpi.com/2079-6374/11/7/230surface-enhanced Raman spectroscopyDNAplasmonicsnanoparticlessensing |
spellingShingle | Irene Calderon Luca Guerrini Ramon A. Alvarez-Puebla Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy Biosensors surface-enhanced Raman spectroscopy DNA plasmonics nanoparticles sensing |
title | Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy |
title_full | Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy |
title_fullStr | Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy |
title_full_unstemmed | Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy |
title_short | Targets and Tools: Nucleic Acids for Surface-Enhanced Raman Spectroscopy |
title_sort | targets and tools nucleic acids for surface enhanced raman spectroscopy |
topic | surface-enhanced Raman spectroscopy DNA plasmonics nanoparticles sensing |
url | https://www.mdpi.com/2079-6374/11/7/230 |
work_keys_str_mv | AT irenecalderon targetsandtoolsnucleicacidsforsurfaceenhancedramanspectroscopy AT lucaguerrini targetsandtoolsnucleicacidsforsurfaceenhancedramanspectroscopy AT ramonaalvarezpuebla targetsandtoolsnucleicacidsforsurfaceenhancedramanspectroscopy |