Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma
Introduction: Remdesivir (GS-5734) is a nucleoside analog prodrug with antiviral activity against several single-stranded RNA viruses, including the novel severe respiratory distress syndrome virus 2 (SARS-CoV-2). It is currently the only FDA-approved antiviral agent for the treatment of individuals...
Main Authors: | Christine Skaggs, Hannah Zimmerman, Nicholas Manicke, Lindsey Kirkpatrick |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-08-01
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Series: | Journal of Mass Spectrometry and Advances in the Clinical Lab |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667145X22000165 |
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