Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes
Background: Children admitted in a pediatric intensive care unit have a high risk of mortality. Pediatric risk of mortality III score in first 24 hours of admission has increasingly been used to predict mortality. The objective of this study was to evaluate the validity of Pediatric risk of mortali...
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| Format: | Article |
| Language: | English |
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Nepal Health Research Council
2024-03-01
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| Series: | Journal of Nepal Health Research Council |
| Online Access: | http://103.69.126.137/index.php/jnhrc/article/view/4662 |
| _version_ | 1797248217288540160 |
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| author | Prakash Joshi Sumit Agrawal Jagat Jeevan Ghimire Pun Narayan Shrestha Najala Khatun Megha Raj Banjara |
| author_facet | Prakash Joshi Sumit Agrawal Jagat Jeevan Ghimire Pun Narayan Shrestha Najala Khatun Megha Raj Banjara |
| author_sort | Prakash Joshi |
| collection | DOAJ |
| description |
Background: Children admitted in a pediatric intensive care unit have a high risk of mortality. Pediatric risk of mortality III score in first 24 hours of admission has increasingly been used to predict mortality. The objective of this study was to evaluate the validity of Pediatric risk of mortality score in prediction of mortality among the patient admitted in pediatric intensive care unit.
Methods: This prospective observational study was conducted at pediatric intensive care unit of a government pediatric hospital from January to June 2021. Patients between 1 month to 14 years of age and meeting the inclusion criteria were enrolled. Pediatric risk of mortality III score was calculated within 24 hours of admission. Patients were followed up for outcome measure as survivors and non survivors. Chi square test and logistic regression analysis were used to find the association of predictors and the score.
Results: The mean Pediatric risk of mortality III score was lower in survivors than in non-survivors (4.67 ± 3.8 versus 14.10 ± 6.07; p<0.001). Those requiring inotropic and ventilator support have significantly higher mortality [49.4 versus 0.6 (p<0.001) and 81.8 versus 1.5 (p<0.001) respectively]. Minimum systolic blood pressure, abnormal pupillary reflex, increased blood urea nitrogen and decreased platelet were the significant (p<0.001) risk factors. The area under the Receiver Operating Characteristic curve was 0.916±0.024 (p<0.001) and goodness-of-fit test showed no significant difference between observed and expected mortalities (p=0.186).
Conclusions: The Pediatric risk of mortality score constitutes a useful prognostic tool in predicting the mortality.
Key words: Mortality; pediatrics; pediatric intensive care unit; risk score,
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| first_indexed | 2024-04-24T20:11:05Z |
| format | Article |
| id | doaj.art-82bd766b55d0471497509ea05a632ef2 |
| institution | Directory Open Access Journal |
| issn | 1727-5482 1999-6217 |
| language | English |
| last_indexed | 2024-04-24T20:11:05Z |
| publishDate | 2024-03-01 |
| publisher | Nepal Health Research Council |
| record_format | Article |
| series | Journal of Nepal Health Research Council |
| spelling | doaj.art-82bd766b55d0471497509ea05a632ef22024-03-23T09:08:50ZengNepal Health Research CouncilJournal of Nepal Health Research Council1727-54821999-62172024-03-0121310.33314/jnhrc.v21i3.4662Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality OutcomesPrakash Joshi0Sumit Agrawal1Jagat Jeevan Ghimire2Pun Narayan Shrestha3Najala Khatun4Megha Raj Banjara 5Department of Pediatric Medicine, Kanti Childrens Hospital, Maharajgunj, Kathmandu, NepalDepartment of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, NepalDepartment of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, NepalDepartment of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, NepalDepartment of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, NepalDepartment of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal Background: Children admitted in a pediatric intensive care unit have a high risk of mortality. Pediatric risk of mortality III score in first 24 hours of admission has increasingly been used to predict mortality. The objective of this study was to evaluate the validity of Pediatric risk of mortality score in prediction of mortality among the patient admitted in pediatric intensive care unit. Methods: This prospective observational study was conducted at pediatric intensive care unit of a government pediatric hospital from January to June 2021. Patients between 1 month to 14 years of age and meeting the inclusion criteria were enrolled. Pediatric risk of mortality III score was calculated within 24 hours of admission. Patients were followed up for outcome measure as survivors and non survivors. Chi square test and logistic regression analysis were used to find the association of predictors and the score. Results: The mean Pediatric risk of mortality III score was lower in survivors than in non-survivors (4.67 ± 3.8 versus 14.10 ± 6.07; p<0.001). Those requiring inotropic and ventilator support have significantly higher mortality [49.4 versus 0.6 (p<0.001) and 81.8 versus 1.5 (p<0.001) respectively]. Minimum systolic blood pressure, abnormal pupillary reflex, increased blood urea nitrogen and decreased platelet were the significant (p<0.001) risk factors. The area under the Receiver Operating Characteristic curve was 0.916±0.024 (p<0.001) and goodness-of-fit test showed no significant difference between observed and expected mortalities (p=0.186). Conclusions: The Pediatric risk of mortality score constitutes a useful prognostic tool in predicting the mortality. Key words: Mortality; pediatrics; pediatric intensive care unit; risk score, http://103.69.126.137/index.php/jnhrc/article/view/4662 |
| spellingShingle | Prakash Joshi Sumit Agrawal Jagat Jeevan Ghimire Pun Narayan Shrestha Najala Khatun Megha Raj Banjara Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes Journal of Nepal Health Research Council |
| title | Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes |
| title_full | Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes |
| title_fullStr | Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes |
| title_full_unstemmed | Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes |
| title_short | Application of Pediatric Risk of Mortality (PRISM) III Score in Predicting Mortality Outcomes |
| title_sort | application of pediatric risk of mortality prism iii score in predicting mortality outcomes |
| url | http://103.69.126.137/index.php/jnhrc/article/view/4662 |
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