Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer
Abstract Background Carbon nanoparticles (CNs) are tracers used in thyroid surgery of patients with thyroid cancer (TC) to help remove lymph nodes and protect the parathyroid gland. The facilitative effect of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection (...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-11-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12957-021-02427-8 |
| _version_ | 1818740401500061696 |
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| author | Jie He Chaojie Zhang Zeyu Zhang Fada Xia |
| author_facet | Jie He Chaojie Zhang Zeyu Zhang Fada Xia |
| author_sort | Jie He |
| collection | DOAJ |
| description | Abstract Background Carbon nanoparticles (CNs) are tracers used in thyroid surgery of patients with thyroid cancer (TC) to help remove lymph nodes and protect the parathyroid gland. The facilitative effect of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection (pCND) has not been reported. Methods The protective effect on parathyroid gland (PG) function and the numbers of identified parathyroid glands and central lymph nodes in endoscopic thyroid surgery through the total mammary areolas approach were compared between the CN and control groups. Results All endoscopic thyroidectomies were successfully completed. No difference was found in either group regarding the general characteristics or operative complications. The mean number of superior PGs and inferior PGs identified in situ or in the dissected central lymph tissues was not different between the groups. The mean number of lymph nodes removed by unilateral CND was greater in the CN group than in the control group. However, there was no difference in the number of harvested lymph nodes when excluding the LNs less than 5 mm, which exhibit an extremely low metastatic rate. Conclusion Carbon nanoparticles do not improve the protective effect on the parathyroid gland, especially the inferior glands, in endoscopic thyroid surgery through the total mammary areolas approach. There is no need to use CNs to facilitate the lymph node harvest in endoscopic prophylactic unilateral CND. |
| first_indexed | 2024-12-18T01:40:09Z |
| format | Article |
| id | doaj.art-82c1575f0b7f4595bba2c3199c694e55 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-18T01:40:09Z |
| publishDate | 2021-11-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-82c1575f0b7f4595bba2c3199c694e552022-12-21T21:25:22ZengBMCWorld Journal of Surgical Oncology1477-78192021-11-011911710.1186/s12957-021-02427-8Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancerJie He0Chaojie Zhang1Zeyu Zhang2Fada Xia3Department of Breast and Thyroid Surgery, Hunan Provincial People’s Hospital (First Affiliated Hospital of Hunan Normal University)Department of Breast and Thyroid Surgery, Hunan Provincial People’s Hospital (First Affiliated Hospital of Hunan Normal University)Department of General Surgery, Xiangya Hospital, Central South UniversityDepartment of General Surgery, Xiangya Hospital, Central South UniversityAbstract Background Carbon nanoparticles (CNs) are tracers used in thyroid surgery of patients with thyroid cancer (TC) to help remove lymph nodes and protect the parathyroid gland. The facilitative effect of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection (pCND) has not been reported. Methods The protective effect on parathyroid gland (PG) function and the numbers of identified parathyroid glands and central lymph nodes in endoscopic thyroid surgery through the total mammary areolas approach were compared between the CN and control groups. Results All endoscopic thyroidectomies were successfully completed. No difference was found in either group regarding the general characteristics or operative complications. The mean number of superior PGs and inferior PGs identified in situ or in the dissected central lymph tissues was not different between the groups. The mean number of lymph nodes removed by unilateral CND was greater in the CN group than in the control group. However, there was no difference in the number of harvested lymph nodes when excluding the LNs less than 5 mm, which exhibit an extremely low metastatic rate. Conclusion Carbon nanoparticles do not improve the protective effect on the parathyroid gland, especially the inferior glands, in endoscopic thyroid surgery through the total mammary areolas approach. There is no need to use CNs to facilitate the lymph node harvest in endoscopic prophylactic unilateral CND.https://doi.org/10.1186/s12957-021-02427-8Endoscopic thyroidectomyProphylactic central neck dissectionCarbon nanoparticles |
| spellingShingle | Jie He Chaojie Zhang Zeyu Zhang Fada Xia Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer World Journal of Surgical Oncology Endoscopic thyroidectomy Prophylactic central neck dissection Carbon nanoparticles |
| title | Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| title_full | Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| title_fullStr | Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| title_full_unstemmed | Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| title_short | Evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| title_sort | evaluation of the clinical value of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection through total mammary areolas approach for thyroid cancer |
| topic | Endoscopic thyroidectomy Prophylactic central neck dissection Carbon nanoparticles |
| url | https://doi.org/10.1186/s12957-021-02427-8 |
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