The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated
The kynurenine pathway has been highlighted as a gatekeeper of immune-privileged sites through its ability to generate from tryptophan a set of immunosuppressive metabolic intermediates. It additionally constitutes an important source of cellular NAD<sup>+</sup> for the organism. Hijacki...
Main Authors: | Roumaïssa Gouasmi, Carole Ferraro-Peyret, Stéphane Nancey, Isabelle Coste, Toufic Renno, Cédric Chaveroux, Nicolas Aznar, Stéphane Ansieau |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/14/11/2793 |
Similar Items
-
Kynurenine acid - metabolism and regulation of kynurenine pathway
by: Piotr Kozłowski, et al.
Published: (2017-07-01) -
Kynurenine Pathway in Psoriasis—a Promising Link?
by: A. Stepaniuk, et al.
Published: (2023-06-01) -
The immunomodulatory role of IDO1-Kynurenine-NAD+ pathway in switching cold tumor microenvironment in PDAC
by: R. I. Anu, et al.
Published: (2023-06-01) -
Metabolic Rewiring of Kynurenine Pathway during Hepatic Ischemia–Reperfusion Injury Exacerbates Liver Damage by Impairing NAD Homeostasis
by: Bowen Xu, et al.
Published: (2022-12-01) -
Different Kynurenine Pathway Dysregulation in Systemic Sclerosis in Men and Women
by: Monika Turska-Kozłowska, et al.
Published: (2024-03-01)