The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated

The kynurenine pathway has been highlighted as a gatekeeper of immune-privileged sites through its ability to generate from tryptophan a set of immunosuppressive metabolic intermediates. It additionally constitutes an important source of cellular NAD<sup>+</sup> for the organism. Hijacki...

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Bibliographic Details
Main Authors: Roumaïssa Gouasmi, Carole Ferraro-Peyret, Stéphane Nancey, Isabelle Coste, Toufic Renno, Cédric Chaveroux, Nicolas Aznar, Stéphane Ansieau
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
NAD
kynurenine
tumor initiation and progression
Online Access:https://www.mdpi.com/2072-6694/14/11/2793

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