Catastrophic complications from filler injection on external genitalia

Soft tissue filler injections are widely used due to their immediate effects, predictable results, and high stability. However, as the use of soft tissue filler injections has increased, various complications have been reported. We report a life-threatening complication in a patient who developed se...

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Main Authors: Byeong Soo Kwon, Jin Woo Kim
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2021-01-01
Series:Archives of Plastic Surgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01907
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author Byeong Soo Kwon
Jin Woo Kim
author_facet Byeong Soo Kwon
Jin Woo Kim
author_sort Byeong Soo Kwon
collection DOAJ
description Soft tissue filler injections are widely used due to their immediate effects, predictable results, and high stability. However, as the use of soft tissue filler injections has increased, various complications have been reported. We report a life-threatening complication in a patient who developed sepsis and necrotizing fasciitis. A 45-year-old woman presented with right leg pain and discharge from the labia majora. The patient had received a soft tissue filler injection of unknown composition 1 year earlier and had recently undergone incision and drainage for an inflammatory cystic nodule. Antibiotic treatment was administered for cellulitis, but the infection progressed to necrotizing fasciitis and sepsis. Fasciotomy and intensive care unit treatment improved the systemic infection, but the soft tissue filler injection site did not respond to treatment for 1 month. Thus, the injection site was covered with a pedicled vertical rectus abdominis musculocutaneous flap after wide excision. The area of skin necrosis on the leg was covered with split-thickness skin grafts. Infections occurring after soft tissue filler injections are related to biofilms, and treatment is sometimes difficult. Therefore, although soft tissue filler injections have a favorable safety profile, it is important to be aware of the risk of life-threatening complications.
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spelling doaj.art-82c3d5789daf45048b96d8ff14cd349d2022-12-22T04:23:45ZengThieme Medical Publishers, Inc.Archives of Plastic Surgery2234-61632234-61712021-01-014801101410.5999/aps.2020.019073807Catastrophic complications from filler injection on external genitaliaByeong Soo Kwon0Jin Woo Kim1Department of Plastic Surgery, Inje University Busan Paik Hospital, Busan, KoreaDepartment of Plastic Surgery, Inje University Busan Paik Hospital, Busan, KoreaSoft tissue filler injections are widely used due to their immediate effects, predictable results, and high stability. However, as the use of soft tissue filler injections has increased, various complications have been reported. We report a life-threatening complication in a patient who developed sepsis and necrotizing fasciitis. A 45-year-old woman presented with right leg pain and discharge from the labia majora. The patient had received a soft tissue filler injection of unknown composition 1 year earlier and had recently undergone incision and drainage for an inflammatory cystic nodule. Antibiotic treatment was administered for cellulitis, but the infection progressed to necrotizing fasciitis and sepsis. Fasciotomy and intensive care unit treatment improved the systemic infection, but the soft tissue filler injection site did not respond to treatment for 1 month. Thus, the injection site was covered with a pedicled vertical rectus abdominis musculocutaneous flap after wide excision. The area of skin necrosis on the leg was covered with split-thickness skin grafts. Infections occurring after soft tissue filler injections are related to biofilms, and treatment is sometimes difficult. Therefore, although soft tissue filler injections have a favorable safety profile, it is important to be aware of the risk of life-threatening complications.http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01907genitaliafasciitis, necrotizingsepsisbiofilms
spellingShingle Byeong Soo Kwon
Jin Woo Kim
Catastrophic complications from filler injection on external genitalia
Archives of Plastic Surgery
genitalia
fasciitis, necrotizing
sepsis
biofilms
title Catastrophic complications from filler injection on external genitalia
title_full Catastrophic complications from filler injection on external genitalia
title_fullStr Catastrophic complications from filler injection on external genitalia
title_full_unstemmed Catastrophic complications from filler injection on external genitalia
title_short Catastrophic complications from filler injection on external genitalia
title_sort catastrophic complications from filler injection on external genitalia
topic genitalia
fasciitis, necrotizing
sepsis
biofilms
url http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01907
work_keys_str_mv AT byeongsookwon catastrophiccomplicationsfromfillerinjectiononexternalgenitalia
AT jinwookim catastrophiccomplicationsfromfillerinjectiononexternalgenitalia