The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up
Abstract Objective To evaluate the efficacy of strength exercise or aerobic exercise compared to usual care on knee-related quality of life (QoL) and knee function at 4 months and 1 year in individuals with knee osteoarthritis. Methods A three-arm randomized controlled trial (RCT) compared 12 weeks...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-023-06831-x |
| _version_ | 1797578606713503744 |
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| author | Britt Elin Øiestad Asbjørn Årøen Jan Harald Røtterud Nina Østerås Even Jarstad Margreth Grotle May Arna Risberg |
| author_facet | Britt Elin Øiestad Asbjørn Årøen Jan Harald Røtterud Nina Østerås Even Jarstad Margreth Grotle May Arna Risberg |
| author_sort | Britt Elin Øiestad |
| collection | DOAJ |
| description | Abstract Objective To evaluate the efficacy of strength exercise or aerobic exercise compared to usual care on knee-related quality of life (QoL) and knee function at 4 months and 1 year in individuals with knee osteoarthritis. Methods A three-arm randomized controlled trial (RCT) compared 12 weeks of strength exercise or aerobic exercise (stationary cycling) to usual care supervised by physiotherapists in primary care. We recruited 168 participants aged 35–70 years with symptomatic knee osteoarthritis. The primary outcome was The Knee Injury and Osteoarthritis Outcome Score (KOOS) QoL at 1 year. Secondary outcomes were self-reported function, pain, and self-efficacy, muscle strength and maximal oxygen uptake (VO2max) at 4 months and 1 year. Results There were no differences between strength exercise and usual care on KOOS QoL (6.5, 95% CI -0.9 to 14), or for aerobic exercise and usual care (5.0, 95% CI -2.7 to 12.8), at 1 year. The two exercise groups showed better quadriceps muscle strength, and VO2max at 4 months, compared to usual care. Conclusion This trial found no statistically significant effects of two exercise programs compared to usual care on KOOS QoL at 1 year in individuals with symptomatic and radiographic knee osteoarthritis, but an underpowered sample size may explain lack of efficacy between the intervention groups and the usual care group. ClinicalTrials.gov Identifier NCT01682980. |
| first_indexed | 2024-03-10T22:24:14Z |
| format | Article |
| id | doaj.art-82c496728df94bcaa7bf5874a0fd99b0 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-03-10T22:24:14Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-82c496728df94bcaa7bf5874a0fd99b02023-11-19T12:09:31ZengBMCBMC Musculoskeletal Disorders1471-24742023-09-0124111210.1186/s12891-023-06831-xThe efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-upBritt Elin Øiestad0Asbjørn Årøen1Jan Harald Røtterud2Nina Østerås3Even Jarstad4Margreth Grotle5May Arna Risberg6Department of Rehabilitation Sciences and Health Technology, Oslo Metropolitan UniversityOrthopedic department, Akershus University HospitalOrthopaedic department, Akershus University HospitalCenter for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet HospitalNorwegian Sports Medicine ClinicDepartment of Rehabilitation Sciences and Health Technology, Oslo Metropolitan UniversityDivision of Orthopedic Surgery, Oslo University HospitalAbstract Objective To evaluate the efficacy of strength exercise or aerobic exercise compared to usual care on knee-related quality of life (QoL) and knee function at 4 months and 1 year in individuals with knee osteoarthritis. Methods A three-arm randomized controlled trial (RCT) compared 12 weeks of strength exercise or aerobic exercise (stationary cycling) to usual care supervised by physiotherapists in primary care. We recruited 168 participants aged 35–70 years with symptomatic knee osteoarthritis. The primary outcome was The Knee Injury and Osteoarthritis Outcome Score (KOOS) QoL at 1 year. Secondary outcomes were self-reported function, pain, and self-efficacy, muscle strength and maximal oxygen uptake (VO2max) at 4 months and 1 year. Results There were no differences between strength exercise and usual care on KOOS QoL (6.5, 95% CI -0.9 to 14), or for aerobic exercise and usual care (5.0, 95% CI -2.7 to 12.8), at 1 year. The two exercise groups showed better quadriceps muscle strength, and VO2max at 4 months, compared to usual care. Conclusion This trial found no statistically significant effects of two exercise programs compared to usual care on KOOS QoL at 1 year in individuals with symptomatic and radiographic knee osteoarthritis, but an underpowered sample size may explain lack of efficacy between the intervention groups and the usual care group. ClinicalTrials.gov Identifier NCT01682980.https://doi.org/10.1186/s12891-023-06831-xKnee osteoarthritisQuality of lifeExercise |
| spellingShingle | Britt Elin Øiestad Asbjørn Årøen Jan Harald Røtterud Nina Østerås Even Jarstad Margreth Grotle May Arna Risberg The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up BMC Musculoskeletal Disorders Knee osteoarthritis Quality of life Exercise |
| title | The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up |
| title_full | The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up |
| title_fullStr | The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up |
| title_full_unstemmed | The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up |
| title_short | The efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis. A multi-arm randomized controlled trial with 1-year follow-up |
| title_sort | efficacy of strength or aerobic exercise on quality of life and knee function in patients with knee osteoarthritis a multi arm randomized controlled trial with 1 year follow up |
| topic | Knee osteoarthritis Quality of life Exercise |
| url | https://doi.org/10.1186/s12891-023-06831-x |
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