p38MAPK guards the integrity of endosomal compartments through regulating necrotic death
Abstract Pathogens trigger activation of sensors of the innate immune system that initiate molecular signaling enabling appropriate host defense programs. Although recognition of pathogen-specific moieties or PAMPs by specialized receptors of the immune system is well defined for a great number of p...
Main Authors: | Jia Yao, Svetlana Atasheva, Randall Toy, Emmeline L. Blanchard, Philip J. Santangelo, Krishnendu Roy, Edward S. Mocarski, Dmitry M. Shayakhmetov |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-20786-4 |
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