An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity

An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity

The inflammatory microenvironment promotes skin tumorigenesis. However, the mechanisms by which cells protect themselves from inflammatory signals are unknown. Downregulation of IKKα promotes skin tumor progression from papillomas to squamous cell carcinomas, which is frequently accompanied by genom...

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Bibliographic Details
Main Authors: Xiaojun Xia, Shuang Liu, Zuoxiang Xiao, Feng Zhu, Na-Young Song, Ming Zhou, Bigang Liu, Jianjun Shen, Kunio Nagashima, Timothy D. Veenstra, Sandra Burkett, Mahesh Datla, Jami Willette-Brown, Haifa Shen, Yinling Hu
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713006451

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