Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans

Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans

Abstract Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method. We assessed the genetic diversity of HLA class I and class II in this population, and determined the most probable ancestry of Lacandon...

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Detalhes bibliográficos
Principais autores: Rodrigo Barquera, Joaquin Zuniga, José Flores-Rivera, Teresa Corona, Bridget S. Penman, Diana Iraíz Hernández-Zaragoza, Manuel Soler, Letisia Jonapá-Gómez, Kalyan C. Mallempati, Petra Yescas, Adriana Ochoa-Morales, Konstantinos Barsakis, José Artemio Aguilar-Vázquez, Maricela García-Lechuga, Michael Mindrinos, María Yunis, Luis Jiménez-Alvarez, Lourdes Mena-Hernández, Esteban Ortega, Alfredo Cruz-Lagunas, Víctor Hugo Tovar-Méndez, Julio Granados, Marcelo Fernández-Viña, Edmond Yunis
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2020-02-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-020-58897-5

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