CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner

CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner

Abstract Background Clinical and experimental studies have shown that the myocardial inflammatory response during pathological events varies between males and females. However, the cellular and molecular mechanisms of these sex differences remain elusive. CD73/adenosine axis has been linked to anti-...

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Bibliographic Details
Main Authors: Marie Louise Ndzie Noah, Richard Mprah, Prosperl Ivette Wowui, Adebayo Oluwafemi Adekunle, Joseph Adu-Amankwaah, Rubin Tan, Zheng Gong, Tao Li, Lu Fu, Jeremiah Ong’achwa Machuki, Shijie Zhang, Hong Sun
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cell Communication and Signaling
Subjects:
Sex differences
Metabolic shift
Inflammation
CD73/adenosine axis
Hypobaric hypoxia
Cardiac dysfunction
Online Access:https://doi.org/10.1186/s12964-024-01535-8

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