Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis
Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum commonly colonize the human urogenital tract, which may cause urogenital infections. However, infection by M. hominis, U. parvum, or U. urealyticum is rarely reported in patients with peritoneal dialysis (PD)-associated peritonitis. H...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S120197122300108X |
| _version_ | 1797851311939518464 |
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| author | Can Wang Jingshuang Wang Juan Yan Feng Chen Ying Zhang Xuelian Hu |
| author_facet | Can Wang Jingshuang Wang Juan Yan Feng Chen Ying Zhang Xuelian Hu |
| author_sort | Can Wang |
| collection | DOAJ |
| description | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum commonly colonize the human urogenital tract, which may cause urogenital infections. However, infection by M. hominis, U. parvum, or U. urealyticum is rarely reported in patients with peritoneal dialysis (PD)-associated peritonitis. Herein, we reported four cases of PD-associated peritonitis caused by these pathogens, along with a review of the literature.The four cases were female patients with recurrent “culture-negative” PD-associated peritonitis and were related to menstruation. M. hominis, U. parvum, or U. urealyticum was detected in the PD fluid of the patients by metagenomic next-generation sequencing. All four patients were cured by intraperitoneal tigecycline combined with oral azithromycin or minocycline.M. hominis, U. parvum, and U. urealyticum should be paid more attention in female patients with recurrent culture-negative PD-associated peritonitis, especially when the peritonitis is related to menstruation, sexual intercourse, or urogenital tract operation. Moreover, metagenomic next-generation sequencing can provide a reasonable method to identify the pathogen for culture-negative PD-associated peritonitis. |
| first_indexed | 2024-04-09T19:15:48Z |
| format | Article |
| id | doaj.art-82cf6f7244df4061a44b32c1cbbc8f84 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-04-09T19:15:48Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-82cf6f7244df4061a44b32c1cbbc8f842023-04-06T06:10:22ZengElsevierInternational Journal of Infectious Diseases1201-97122023-06-011311315Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitisCan Wang0Jingshuang Wang1Juan Yan2Feng Chen3Ying Zhang4Xuelian Hu5Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Nephrology, The Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Nephrology, The People's Hospital of Liangping, Chongqing, ChinaDepartment of Nephrology, The Second Affiliated Hospital of Army Medical University, Chongqing, ChinaDepartment of Nephrology, The Second Affiliated Hospital of Army Medical University, Chongqing, China; Corresponding authors.Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, Chongqing, China; Corresponding authors.Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum commonly colonize the human urogenital tract, which may cause urogenital infections. However, infection by M. hominis, U. parvum, or U. urealyticum is rarely reported in patients with peritoneal dialysis (PD)-associated peritonitis. Herein, we reported four cases of PD-associated peritonitis caused by these pathogens, along with a review of the literature.The four cases were female patients with recurrent “culture-negative” PD-associated peritonitis and were related to menstruation. M. hominis, U. parvum, or U. urealyticum was detected in the PD fluid of the patients by metagenomic next-generation sequencing. All four patients were cured by intraperitoneal tigecycline combined with oral azithromycin or minocycline.M. hominis, U. parvum, and U. urealyticum should be paid more attention in female patients with recurrent culture-negative PD-associated peritonitis, especially when the peritonitis is related to menstruation, sexual intercourse, or urogenital tract operation. Moreover, metagenomic next-generation sequencing can provide a reasonable method to identify the pathogen for culture-negative PD-associated peritonitis.http://www.sciencedirect.com/science/article/pii/S120197122300108XMycoplasma hominisUreaplasma parvumUreaplasma urealyticumPeritonitisPeritoneal dialysisMetagenomic next-generation sequencing |
| spellingShingle | Can Wang Jingshuang Wang Juan Yan Feng Chen Ying Zhang Xuelian Hu Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis International Journal of Infectious Diseases Mycoplasma hominis Ureaplasma parvum Ureaplasma urealyticum Peritonitis Peritoneal dialysis Metagenomic next-generation sequencing |
| title | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis |
| title_full | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis |
| title_fullStr | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis |
| title_full_unstemmed | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis |
| title_short | Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum: hidden pathogens in peritoneal dialysis-associated peritonitis |
| title_sort | mycoplasma hominis ureaplasma parvum and ureaplasma urealyticum hidden pathogens in peritoneal dialysis associated peritonitis |
| topic | Mycoplasma hominis Ureaplasma parvum Ureaplasma urealyticum Peritonitis Peritoneal dialysis Metagenomic next-generation sequencing |
| url | http://www.sciencedirect.com/science/article/pii/S120197122300108X |
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