Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1

Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1

Pulmonary arterial hypertension (PAH) is a chronic obstructive disease characterized by vascular remodeling. Studies have confirmed that ginsenoside Rg1 can improve pulmonary hypertension to a certain extent, but the potential mechanism by which it improves hypoxia-induced PAH remains unclear. The a...

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Bibliographic Details
Main Authors: Bai-lin Tang, Yu Liu, Jing-liang Zhang, Mei-li Lu, Hong-xin Wang
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ginsenoside Rg1
Pulmonary arterial hypertension
Endothelial-to-mesenchymal transition
Inflammation
CCN1
Hypoxia
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223007102

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http://www.sciencedirect.com/science/article/pii/S0753332223007102

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