Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1
Pulmonary arterial hypertension (PAH) is a chronic obstructive disease characterized by vascular remodeling. Studies have confirmed that ginsenoside Rg1 can improve pulmonary hypertension to a certain extent, but the potential mechanism by which it improves hypoxia-induced PAH remains unclear. The a...
Main Authors: | Bai-lin Tang, Yu Liu, Jing-liang Zhang, Mei-li Lu, Hong-xin Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-08-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332223007102 |
Similar Items
-
Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition
by: Eunsik Yun, et al.
Published: (2023-12-01) -
Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway
by: Fang Zhao, et al.
Published: (2023-01-01) -
Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells
by: Fang He, et al.
Published: (2020-01-01) -
Ginsenoside Rg1 promotes endothelialization of tissue-engineered blood vessels in transplanted rats
by: WANG Tianran, et al.
Published: (2020-03-01) -
Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats
by: Qin Q, et al.
Published: (2019-07-01)