Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup
Introduction. This study determines the incidence of common viral and helminth coinfections with malaria in the tertiary care hospital set up in southern Khyber Pakhtunkhwa, Pakistan. Materials and Methods. The multidimensional research included malaria patients admitted to different hospitals of di...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2024-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2024/8529788 |
| _version_ | 1827079504349102080 |
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| author | Murad A. Mubaraki Mubbashir Hussain Fozia Fozia Ijaz Ahmad Shahid Niaz Khan Abdul Qadir Khan Ziaullah Ziaullah |
| author_facet | Murad A. Mubaraki Mubbashir Hussain Fozia Fozia Ijaz Ahmad Shahid Niaz Khan Abdul Qadir Khan Ziaullah Ziaullah |
| author_sort | Murad A. Mubaraki |
| collection | DOAJ |
| description | Introduction. This study determines the incidence of common viral and helminth coinfections with malaria in the tertiary care hospital set up in southern Khyber Pakhtunkhwa, Pakistan. Materials and Methods. The multidimensional research included malaria patients admitted to different hospitals of district Kohat during January and December 2021. Stool samples and blood were assembled from the patients. Giemsa-stained microscopy-positive samples were processed by the immunochromatography technique (ICT) to identify Plasmodium species. Common viral infections such as viral hepatitis (A, B, and C), HIV, and dengue (DENV) were analyzed by ICT kits while SARS-CoV-2 was confirmed through real-time PCR. Furthermore, the intestinal helminths were identified using the Kato-Katz thick smear method. Results. Among 1278 patients, 548 were diagnosed with malaria, 412 (75.2%) were positive for P. vivax infection, 115 (21%) for P. falciparum, and 21 (3.8%) for mixed malaria infection (P. vivax/P. falciparum), with a higher incidence among males (65.2%) than females (34.8%). Coinfection with helminths was positive in 215 (39.3%) malaria patients. The most common infections were caused by the Ascaris lumbricoides species (42.6%) followed by Enterobius vermicularis (31.7%) and hookworm. A total of 24.6% of malaria-positive cases were also coinfected with different viruses with higher frequencies of confection for HAV (8.2%) and DENV (6.2%), respectively. The patients revealed higher incidence of coinfections with P. falciparum (57%) as compared with P. vivax (39.2%) and mixed infections (3.7%). Conclusion. This study demonstrated that the study population exhibited a significant incidence of coinfections with intestinal helminth and viral malaria. |
| first_indexed | 2024-04-24T13:14:03Z |
| format | Article |
| id | doaj.art-82d47a2b490b4b8c8df0f0ec20d2efcc |
| institution | Directory Open Access Journal |
| issn | 1687-9694 |
| language | English |
| last_indexed | 2025-03-20T02:46:37Z |
| publishDate | 2024-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj.art-82d47a2b490b4b8c8df0f0ec20d2efcc2024-10-03T07:30:06ZengHindawi LimitedJournal of Tropical Medicine1687-96942024-01-01202410.1155/2024/8529788Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital SetupMurad A. Mubaraki0Mubbashir Hussain1Fozia Fozia2Ijaz Ahmad3Shahid Niaz Khan4Abdul Qadir Khan5Ziaullah Ziaullah6Clinical Laboratory Sciences DepartmentDepartment of MicrobiologyDepartment of BiochemistryDepartment of ChemistryDepartment of ZoologyDepartment of MicrobiologyCollege of Professional StudiesIntroduction. This study determines the incidence of common viral and helminth coinfections with malaria in the tertiary care hospital set up in southern Khyber Pakhtunkhwa, Pakistan. Materials and Methods. The multidimensional research included malaria patients admitted to different hospitals of district Kohat during January and December 2021. Stool samples and blood were assembled from the patients. Giemsa-stained microscopy-positive samples were processed by the immunochromatography technique (ICT) to identify Plasmodium species. Common viral infections such as viral hepatitis (A, B, and C), HIV, and dengue (DENV) were analyzed by ICT kits while SARS-CoV-2 was confirmed through real-time PCR. Furthermore, the intestinal helminths were identified using the Kato-Katz thick smear method. Results. Among 1278 patients, 548 were diagnosed with malaria, 412 (75.2%) were positive for P. vivax infection, 115 (21%) for P. falciparum, and 21 (3.8%) for mixed malaria infection (P. vivax/P. falciparum), with a higher incidence among males (65.2%) than females (34.8%). Coinfection with helminths was positive in 215 (39.3%) malaria patients. The most common infections were caused by the Ascaris lumbricoides species (42.6%) followed by Enterobius vermicularis (31.7%) and hookworm. A total of 24.6% of malaria-positive cases were also coinfected with different viruses with higher frequencies of confection for HAV (8.2%) and DENV (6.2%), respectively. The patients revealed higher incidence of coinfections with P. falciparum (57%) as compared with P. vivax (39.2%) and mixed infections (3.7%). Conclusion. This study demonstrated that the study population exhibited a significant incidence of coinfections with intestinal helminth and viral malaria.http://dx.doi.org/10.1155/2024/8529788 |
| spellingShingle | Murad A. Mubaraki Mubbashir Hussain Fozia Fozia Ijaz Ahmad Shahid Niaz Khan Abdul Qadir Khan Ziaullah Ziaullah Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup Journal of Tropical Medicine |
| title | Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup |
| title_full | Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup |
| title_fullStr | Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup |
| title_full_unstemmed | Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup |
| title_short | Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup |
| title_sort | incidence of helminthic and viral coinfections in malaria patients in the tertiary care hospital setup |
| url | http://dx.doi.org/10.1155/2024/8529788 |
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