Daily Variations of Corneal White-to-White Diameter Measured with Different Methods

Stefan Bandlitz,1,2 Makram Nakhoul,3 Konstantin Kotliar3 1Höhere Fachschule für Augenoptik Köln (HFAK), Cologne School of Optometry, Cologne, Germany; 2School of Life and Health Sciences, Aston University, Birmingham, UK; 3Department of Medical Engineering and Technomathematics, FH Aachen University...

Full description

Bibliographic Details
Main Authors: Bandlitz S, Nakhoul M, Kotliar K
Format: Article
Language:English
Published: Dove Medical Press 2022-09-01
Series:Clinical Optometry
Subjects:
Online Access:https://www.dovepress.com/daily-variations-of-corneal-white-to-white-diameter-measured-with-diff-peer-reviewed-fulltext-article-OPTO
_version_ 1798035448052842496
author Bandlitz S
Nakhoul M
Kotliar K
author_facet Bandlitz S
Nakhoul M
Kotliar K
author_sort Bandlitz S
collection DOAJ
description Stefan Bandlitz,1,2 Makram Nakhoul,3 Konstantin Kotliar3 1Höhere Fachschule für Augenoptik Köln (HFAK), Cologne School of Optometry, Cologne, Germany; 2School of Life and Health Sciences, Aston University, Birmingham, UK; 3Department of Medical Engineering and Technomathematics, FH Aachen University of Applied Sciences, Campus Jülich, Jülich, 52428, GermanyCorrespondence: Konstantin Kotliar, Department of Medical Engineering and Technomathematics, FH Aachen University of Applied Sciences, Campus Jülich, Heinrich-Mussmann-Str. 1, Jülich, 52428, Germany, Tel +49 241 6009-53812, Fax +49 241 6009-53222, Email kotliar@fh-aachen.dePurpose: A precise determination of the corneal diameter is essential for the diagnosis of various ocular diseases, cataract and refractive surgery as well as for the selection and fitting of contact lenses. The aim of this study was to investigate the agreement between two automatic and one manual method for corneal diameter determination and to evaluate possible diurnal variations in corneal diameter.Patients and Methods: Horizontal white-to-white corneal diameter of 20 volunteers was measured at three different fixed times of a day with three methods: Scheimpflug method (Pentacam HR, Oculus), placido based topography (Keratograph 5M, Oculus) and manual method using an image analysis software at a slitlamp (BQ900, Haag-Streit).Results: The two-factorial analysis of variance could not show a significant effect of the different instruments (p = 0.117), the different time points (p = 0.506) and the interaction between instrument and time point (p = 0.182). Very good repeatability (intraclass correlation coefficient ICC, quartile coefficient of dispersion QCD) was found for all three devices. However, manual slitlamp measurements showed a higher QCD than the automatic measurements with the Keratograph 5M and the Pentacam HR at all measurement times.Conclusion: The manual and automated methods used in the study to determine corneal diameter showed good agreement and repeatability. No significant diurnal variations of corneal diameter were observed during the period of time studied.Keywords: corneal diameter, white-to-white, diurnal variation, Scheimpflug imaging, placido based topography, slitlamp
first_indexed 2024-04-11T20:58:27Z
format Article
id doaj.art-82d50079bdd740048cbfb6b844500244
institution Directory Open Access Journal
issn 1179-2752
language English
last_indexed 2024-04-11T20:58:27Z
publishDate 2022-09-01
publisher Dove Medical Press
record_format Article
series Clinical Optometry
spelling doaj.art-82d50079bdd740048cbfb6b8445002442022-12-22T04:03:36ZengDove Medical PressClinical Optometry1179-27522022-09-01Volume 1417318178386Daily Variations of Corneal White-to-White Diameter Measured with Different MethodsBandlitz SNakhoul MKotliar KStefan Bandlitz,1,2 Makram Nakhoul,3 Konstantin Kotliar3 1Höhere Fachschule für Augenoptik Köln (HFAK), Cologne School of Optometry, Cologne, Germany; 2School of Life and Health Sciences, Aston University, Birmingham, UK; 3Department of Medical Engineering and Technomathematics, FH Aachen University of Applied Sciences, Campus Jülich, Jülich, 52428, GermanyCorrespondence: Konstantin Kotliar, Department of Medical Engineering and Technomathematics, FH Aachen University of Applied Sciences, Campus Jülich, Heinrich-Mussmann-Str. 1, Jülich, 52428, Germany, Tel +49 241 6009-53812, Fax +49 241 6009-53222, Email kotliar@fh-aachen.dePurpose: A precise determination of the corneal diameter is essential for the diagnosis of various ocular diseases, cataract and refractive surgery as well as for the selection and fitting of contact lenses. The aim of this study was to investigate the agreement between two automatic and one manual method for corneal diameter determination and to evaluate possible diurnal variations in corneal diameter.Patients and Methods: Horizontal white-to-white corneal diameter of 20 volunteers was measured at three different fixed times of a day with three methods: Scheimpflug method (Pentacam HR, Oculus), placido based topography (Keratograph 5M, Oculus) and manual method using an image analysis software at a slitlamp (BQ900, Haag-Streit).Results: The two-factorial analysis of variance could not show a significant effect of the different instruments (p = 0.117), the different time points (p = 0.506) and the interaction between instrument and time point (p = 0.182). Very good repeatability (intraclass correlation coefficient ICC, quartile coefficient of dispersion QCD) was found for all three devices. However, manual slitlamp measurements showed a higher QCD than the automatic measurements with the Keratograph 5M and the Pentacam HR at all measurement times.Conclusion: The manual and automated methods used in the study to determine corneal diameter showed good agreement and repeatability. No significant diurnal variations of corneal diameter were observed during the period of time studied.Keywords: corneal diameter, white-to-white, diurnal variation, Scheimpflug imaging, placido based topography, slitlamphttps://www.dovepress.com/daily-variations-of-corneal-white-to-white-diameter-measured-with-diff-peer-reviewed-fulltext-article-OPTOcorneal diameterwhite-to-whitediurnal variationscheimpflug imagingplacido based topographyslitlamp
spellingShingle Bandlitz S
Nakhoul M
Kotliar K
Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
Clinical Optometry
corneal diameter
white-to-white
diurnal variation
scheimpflug imaging
placido based topography
slitlamp
title Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
title_full Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
title_fullStr Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
title_full_unstemmed Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
title_short Daily Variations of Corneal White-to-White Diameter Measured with Different Methods
title_sort daily variations of corneal white to white diameter measured with different methods
topic corneal diameter
white-to-white
diurnal variation
scheimpflug imaging
placido based topography
slitlamp
url https://www.dovepress.com/daily-variations-of-corneal-white-to-white-diameter-measured-with-diff-peer-reviewed-fulltext-article-OPTO
work_keys_str_mv AT bandlitzs dailyvariationsofcornealwhitetowhitediametermeasuredwithdifferentmethods
AT nakhoulm dailyvariationsofcornealwhitetowhitediametermeasuredwithdifferentmethods
AT kotliark dailyvariationsofcornealwhitetowhitediametermeasuredwithdifferentmethods