Influence of CYP2C19 genetic variants and smoking on dual antiplatelet efficacy in patients with coronary artery disease

Influence of CYP2C19 genetic variants and smoking on dual antiplatelet efficacy in patients with coronary artery disease

IntroductionThis study aimed to investigate the effects of smoking and CYP2C19 gene polymorphism on antiplatelet therapy to specify the most optimized and accurate antiplatelet therapy for different populations.MethodsThis study included 6,353 patients with coronary artery disease (CAD). In total, 2...

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Bibliographic Details
Main Authors: Yujing Cheng, Yan Sun, Dai Zhang, Xiaoteng Ma, Chi Liu, Chengping Hu, Tienan Sun, Ziwei Zhao, Xiaoli Liu, Yujie Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
coronary artery disease
antiplatelet therapy
clopidogrel
CYP2C19
smoking
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1105001/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1105001/full

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