Computational Fluid Dynamics in Unruptured Intracranial Aneurysms
Introduction and Objective: Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery causes a localized dilation or ballooning of the blood vessel. There is no objective way, device or tools, of predicting rupture of aneury...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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London Academic Publishing
2018-06-01
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| Series: | Romanian Neurosurgery |
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| Online Access: | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1099 |
| _version_ | 1818759134503239680 |
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| author | Maruf Matmusaev Yasuhiro Yamada Tsukasa Kawase Riki Tanaka Miyatani Kyosuke Yoko Kato Ahmed Ansari |
| author_facet | Maruf Matmusaev Yasuhiro Yamada Tsukasa Kawase Riki Tanaka Miyatani Kyosuke Yoko Kato Ahmed Ansari |
| author_sort | Maruf Matmusaev |
| collection | DOAJ |
| description | Introduction and Objective: Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery causes a localized dilation or ballooning of the blood vessel. There is no objective way, device or tools, of predicting rupture of aneurysm so far. Computational fluid dynamics (CFDs) was proposed as a tool to identify the rupture risk. Purpose of study: To reveal the correlation of CFD findings with intraoperative microscopic findings and prove the relevance of CFDin the prediction of rupture risk and in the management of unruptured intracranial aneurysms. Subjects and Methods: A prospective cohort study was conducted inNeurosurgery department of Fujita Health University Banbuntane Hotokukai Hospital, Nagoya, Japanduring a 3‑month period in 2018,from January to March, Ten patientswere diagnosed unruptured intracranial aneurysms (UIA). In diagnosis computed tomography (CT) angiogram, CFD and digital subtraction angiogram were included. Intraoperatively microscopic examination of the aneurysm wall was carried out and images recorded. The correlation between microscopic dome morphology and CFD information was performed. Results: Nine cases were found intraoperatively to have a higher risk of rupture based on the thinning of the wall. One cases had an atherosclerotic wall. All cases had low wall shear stress (WSS). In 90 % of cases Low WSS was able to predict the potency rupture risk in the near future. Conclusions: This study of CFD and its correlation with intraoperativefindings of the aneurysm suggested that low WSS of the aneurysm wall is associated with thin wall aneurysm and hence increased risk of aneurysm rupture. Thus CFD can be used to predict the risk of rupture of unruptured aneurysm and for planning of its treatment. |
| first_indexed | 2024-12-18T06:37:54Z |
| format | Article |
| id | doaj.art-82db97fd1390420fbb04d36eab9b8774 |
| institution | Directory Open Access Journal |
| issn | 1220-8841 2344-4959 |
| language | English |
| last_indexed | 2024-12-18T06:37:54Z |
| publishDate | 2018-06-01 |
| publisher | London Academic Publishing |
| record_format | Article |
| series | Romanian Neurosurgery |
| spelling | doaj.art-82db97fd1390420fbb04d36eab9b87742022-12-21T21:17:44ZengLondon Academic PublishingRomanian Neurosurgery1220-88412344-49592018-06-01322Computational Fluid Dynamics in Unruptured Intracranial AneurysmsMaruf MatmusaevYasuhiro YamadaTsukasa KawaseRiki TanakaMiyatani KyosukeYoko KatoAhmed AnsariIntroduction and Objective: Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in the wall of a cerebral artery causes a localized dilation or ballooning of the blood vessel. There is no objective way, device or tools, of predicting rupture of aneurysm so far. Computational fluid dynamics (CFDs) was proposed as a tool to identify the rupture risk. Purpose of study: To reveal the correlation of CFD findings with intraoperative microscopic findings and prove the relevance of CFDin the prediction of rupture risk and in the management of unruptured intracranial aneurysms. Subjects and Methods: A prospective cohort study was conducted inNeurosurgery department of Fujita Health University Banbuntane Hotokukai Hospital, Nagoya, Japanduring a 3‑month period in 2018,from January to March, Ten patientswere diagnosed unruptured intracranial aneurysms (UIA). In diagnosis computed tomography (CT) angiogram, CFD and digital subtraction angiogram were included. Intraoperatively microscopic examination of the aneurysm wall was carried out and images recorded. The correlation between microscopic dome morphology and CFD information was performed. Results: Nine cases were found intraoperatively to have a higher risk of rupture based on the thinning of the wall. One cases had an atherosclerotic wall. All cases had low wall shear stress (WSS). In 90 % of cases Low WSS was able to predict the potency rupture risk in the near future. Conclusions: This study of CFD and its correlation with intraoperativefindings of the aneurysm suggested that low WSS of the aneurysm wall is associated with thin wall aneurysm and hence increased risk of aneurysm rupture. Thus CFD can be used to predict the risk of rupture of unruptured aneurysm and for planning of its treatment.https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1099computational flow dynamicsintraoperative microscopic findingsunruptured intracranial aneurysms |
| spellingShingle | Maruf Matmusaev Yasuhiro Yamada Tsukasa Kawase Riki Tanaka Miyatani Kyosuke Yoko Kato Ahmed Ansari Computational Fluid Dynamics in Unruptured Intracranial Aneurysms Romanian Neurosurgery computational flow dynamics intraoperative microscopic findings unruptured intracranial aneurysms |
| title | Computational Fluid Dynamics in Unruptured Intracranial Aneurysms |
| title_full | Computational Fluid Dynamics in Unruptured Intracranial Aneurysms |
| title_fullStr | Computational Fluid Dynamics in Unruptured Intracranial Aneurysms |
| title_full_unstemmed | Computational Fluid Dynamics in Unruptured Intracranial Aneurysms |
| title_short | Computational Fluid Dynamics in Unruptured Intracranial Aneurysms |
| title_sort | computational fluid dynamics in unruptured intracranial aneurysms |
| topic | computational flow dynamics intraoperative microscopic findings unruptured intracranial aneurysms |
| url | https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1099 |
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