Dynamin 1 regulates amyloid generation through modulation of BACE-1.

Dynamin 1 regulates amyloid generation through modulation of BACE-1.

BACKGROUND: Several lines of investigation support the notion that endocytosis is crucial for Alzheimer's disease (AD) pathogenesis. Substantial evidence have already been reported regarding the mechanisms underlying amyloid precursor protein (APP) traffic, but the regulation of beta-site APP-C...

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Bibliographic Details
Main Authors:	Li Zhu, Meng Su, Louise Lucast, Lijuan Liu, William J Netzer, Samuel E Gandy, Dongming Cai
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3443198?pdf=render

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