Time-Course Investigation of Small Molecule Metabolites in MAP-Stored Red Blood Cells Using UPLC-QTOF-MS

Time-Course Investigation of Small Molecule Metabolites in MAP-Stored Red Blood Cells Using UPLC-QTOF-MS

Red blood cells (RBCs) are routinely stored for 35 to 42 days in most countries. During storage, RBCs undergo biochemical and biophysical changes known as RBC storage lesion, which is influenced by alternative storage additive solutions (ASs). Metabolomic studies have been completed on RBCs stored i...

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Bibliographic Details
Main Authors: Yong Zhou, Zhiyun Meng, Hui Gan, Ying Zheng, Xiaoxia Zhu, Zhuona Wu, Jian Li, Ruolan Gu, Guifang Dou
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
red blood cells
MAP
UPLC-QTOF-MS
metabolomics
oxidative stress
storage lesion
Online Access:http://www.mdpi.com/1420-3049/23/4/923

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