Using mitoribosomal profiling to investigate human mitochondrial translation [version 2; referees: 2 approved]

Using mitoribosomal profiling to investigate human mitochondrial translation [version 2; referees: 2 approved]

Background: Gene expression in human mitochondria has various idiosyncratic features. One of these was recently revealed as the unprecedented recruitment of a mitochondrially-encoded tRNA as a structural component of the large mitoribosomal subunit. In porcine particles this is mt-tRNAPhe whilst in...

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Bibliographic Details
Main Authors: Fei Gao, Maria Wesolowska, Reuven Agami, Koos Rooijers, Fabricio Loayza-Puch, Conor Lawless, Robert N. Lightowlers, Zofia M. A. Chrzanowska-Lightowlers
Format: Article
Language:English
Published: Wellcome 2018-01-01
Series:Wellcome Open Research
Subjects:
Experimental Biophysical Methods
Genomics
Online Access:https://wellcomeopenresearch.org/articles/2-116/v2

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