CENTRAL HYPOTHROIDISM DUE TO ACUTE LYMPHOBLASTIC LEUKEMIA WITH CENTRAL NERVOUS SYSTEM INFILTRATION
Case report: We describe a five-year-old girl with high risk B precursor acute lymphoblastic leukemia with central nervous system involvement. Laboratory tests suggested the presence of central hypothyroidism (thyroid-stimulating hormone [TSH]: 0.30 mU/ml, normal range 0.64–6.27 mU/ml; serum free th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S253113792101227X |
| Summary: | Case report: We describe a five-year-old girl with high risk B precursor acute lymphoblastic leukemia with central nervous system involvement. Laboratory tests suggested the presence of central hypothyroidism (thyroid-stimulating hormone [TSH]: 0.30 mU/ml, normal range 0.64–6.27 mU/ml; serum free thyroxine [FT4]: 0.70 ng/dl, normal range 0.86–1.4 ng/dl). Magnetic resonance imaging detected heterogeneous contrast enhancement of pituitary gland in addition to cerebral and cerebellar atrophy. |
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| ISSN: | 2531-1379 |