Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview
Over the past few decades, many pathogenic bacteria have become resistant to existing antibiotics, which has become a threat to infectious disease control worldwide. Hence, there has been an extensive search for new, efficient, and alternative sources of antimicrobial agents to combat multidrug-resi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/5/1058 |
| _version_ | 1818583471591784448 |
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| author | Nagaraj Basavegowda Jayanta Kumar Patra Kwang-Hyun Baek |
| author_facet | Nagaraj Basavegowda Jayanta Kumar Patra Kwang-Hyun Baek |
| author_sort | Nagaraj Basavegowda |
| collection | DOAJ |
| description | Over the past few decades, many pathogenic bacteria have become resistant to existing antibiotics, which has become a threat to infectious disease control worldwide. Hence, there has been an extensive search for new, efficient, and alternative sources of antimicrobial agents to combat multidrug-resistant pathogenic microorganisms. Numerous studies have reported the potential of both essential oils and metal/metal oxide nanocomposites with broad spectra of bioactivities including antioxidant, anticancer, and antimicrobial attributes. However, only monometallic nanoparticles combined with essential oils have been reported on so far with limited data. Bi- and tri-metallic nanoparticles have attracted immense attention because of their diverse sizes, shapes, high surface-to-volume ratios, activities, physical and chemical stability, and greater degree of selectivity. Combination therapy is currently blooming and represents a potential area that requires greater attention and is worthy of future investigations. This review summarizes the synergistic effects of essential oils with other antimicrobial combinations such as mono-, bi-, and tri-metallic nanocomposites. Thus, the various aspects of this comprehensive review may prove useful in the development of new and alternative therapeutics against antibiotic resistant pathogens in the future. |
| first_indexed | 2024-12-16T08:05:49Z |
| format | Article |
| id | doaj.art-82e684a6c18e412b9d3c4dc88e78c092 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-16T08:05:49Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-82e684a6c18e412b9d3c4dc88e78c0922022-12-21T22:38:28ZengMDPI AGMolecules1420-30492020-02-01255105810.3390/molecules25051058molecules25051058Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An OverviewNagaraj Basavegowda0Jayanta Kumar Patra1Kwang-Hyun Baek2Department of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 38451, KoreaResearch Institute of Biotechnology and Medical Converged Science, Dongguk University-Seoul, Goyang 10326, KoreaDepartment of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk 38451, KoreaOver the past few decades, many pathogenic bacteria have become resistant to existing antibiotics, which has become a threat to infectious disease control worldwide. Hence, there has been an extensive search for new, efficient, and alternative sources of antimicrobial agents to combat multidrug-resistant pathogenic microorganisms. Numerous studies have reported the potential of both essential oils and metal/metal oxide nanocomposites with broad spectra of bioactivities including antioxidant, anticancer, and antimicrobial attributes. However, only monometallic nanoparticles combined with essential oils have been reported on so far with limited data. Bi- and tri-metallic nanoparticles have attracted immense attention because of their diverse sizes, shapes, high surface-to-volume ratios, activities, physical and chemical stability, and greater degree of selectivity. Combination therapy is currently blooming and represents a potential area that requires greater attention and is worthy of future investigations. This review summarizes the synergistic effects of essential oils with other antimicrobial combinations such as mono-, bi-, and tri-metallic nanocomposites. Thus, the various aspects of this comprehensive review may prove useful in the development of new and alternative therapeutics against antibiotic resistant pathogens in the future.https://www.mdpi.com/1420-3049/25/5/1058essential oilbi-metallic nanoparticlestri-metallic nanoparticlessynergistic effectantimicrobial activitiesmultidrug-resistant pathogens |
| spellingShingle | Nagaraj Basavegowda Jayanta Kumar Patra Kwang-Hyun Baek Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview Molecules essential oil bi-metallic nanoparticles tri-metallic nanoparticles synergistic effect antimicrobial activities multidrug-resistant pathogens |
| title | Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview |
| title_full | Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview |
| title_fullStr | Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview |
| title_full_unstemmed | Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview |
| title_short | Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview |
| title_sort | essential oils and mono bi tri metallic nanocomposites as alternative sources of antimicrobial agents to combat multidrug resistant pathogenic microorganisms an overview |
| topic | essential oil bi-metallic nanoparticles tri-metallic nanoparticles synergistic effect antimicrobial activities multidrug-resistant pathogens |
| url | https://www.mdpi.com/1420-3049/25/5/1058 |
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