PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY
The oral cavity represents an area access zone from the external environment to the internal areas of the body and saliva is at the interface between microbial ecosystems and oral immune cells. Any imbalance of saliva physiology has an impact on oral and systemic health. Elevated inflammatory cytoki...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Romanian Dental Association for Education
2020-12-01
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| Series: | Romanian Journal of Medical and Dental Education |
| Subjects: | |
| Online Access: | http://www.journal.adre.ro/particularities-of-some-endogenous-substances-with-humoral-defense-role-in-the-oral-cavity/ |
| _version_ | 1819116481961525248 |
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| author | Loredana Liliana Hurjui Ion Hurjui Cristina Claudia Tărniceriu Mihaela Mitrea Andrei Ion Hurjui Ruxandra Maria Hârțan Diana Popovici Carina Balcoș Oana Adina Armencia Irina Grădinaru |
| author_facet | Loredana Liliana Hurjui Ion Hurjui Cristina Claudia Tărniceriu Mihaela Mitrea Andrei Ion Hurjui Ruxandra Maria Hârțan Diana Popovici Carina Balcoș Oana Adina Armencia Irina Grădinaru |
| author_sort | Loredana Liliana Hurjui |
| collection | DOAJ |
| description | The oral cavity represents an area access zone from the external environment to the internal areas of the body and saliva is at the interface between microbial ecosystems and oral immune cells. Any imbalance of saliva physiology has an impact on oral and systemic health. Elevated inflammatory cytokines in saliva, for example, activates dysbiosis (disease) of periodontal tissues, feeding forward tissue inflammation, leading to oral tissue loss. Host–microbiome interactions complex modulate pathological transitions including gingivitis, periodontal diseases, and oral cancer. However, mechanisms involving these interactions are poorly understood at the molecular level. |
| first_indexed | 2024-12-22T05:17:47Z |
| format | Article |
| id | doaj.art-82e72003d5b7410581acec0770610d99 |
| institution | Directory Open Access Journal |
| issn | 2393-1108 2393-1531 |
| language | English |
| last_indexed | 2024-12-22T05:17:47Z |
| publishDate | 2020-12-01 |
| publisher | Romanian Dental Association for Education |
| record_format | Article |
| series | Romanian Journal of Medical and Dental Education |
| spelling | doaj.art-82e72003d5b7410581acec0770610d992022-12-21T18:37:49ZengRomanian Dental Association for EducationRomanian Journal of Medical and Dental Education2393-11082393-15312020-12-01966871PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITYLoredana Liliana Hurjui0Ion Hurjui1Cristina Claudia Tărniceriu2Mihaela Mitrea3Andrei Ion Hurjui4Ruxandra Maria Hârțan5Diana Popovici6Carina Balcoș7Oana Adina Armencia8Irina Grădinaru9Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of MedicineGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of DentistryGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of DentistryGrigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania, Faculty of DentistryThe oral cavity represents an area access zone from the external environment to the internal areas of the body and saliva is at the interface between microbial ecosystems and oral immune cells. Any imbalance of saliva physiology has an impact on oral and systemic health. Elevated inflammatory cytokines in saliva, for example, activates dysbiosis (disease) of periodontal tissues, feeding forward tissue inflammation, leading to oral tissue loss. Host–microbiome interactions complex modulate pathological transitions including gingivitis, periodontal diseases, and oral cancer. However, mechanisms involving these interactions are poorly understood at the molecular level.http://www.journal.adre.ro/particularities-of-some-endogenous-substances-with-humoral-defense-role-in-the-oral-cavity/oral cavityinflammatory cytokinessystemic health. |
| spellingShingle | Loredana Liliana Hurjui Ion Hurjui Cristina Claudia Tărniceriu Mihaela Mitrea Andrei Ion Hurjui Ruxandra Maria Hârțan Diana Popovici Carina Balcoș Oana Adina Armencia Irina Grădinaru PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY Romanian Journal of Medical and Dental Education oral cavity inflammatory cytokines systemic health. |
| title | PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY |
| title_full | PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY |
| title_fullStr | PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY |
| title_full_unstemmed | PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY |
| title_short | PARTICULARITIES OF SOME ENDOGENOUS SUBSTANCES WITH HUMORAL DEFENSE ROLE IN THE ORAL CAVITY |
| title_sort | particularities of some endogenous substances with humoral defense role in the oral cavity |
| topic | oral cavity inflammatory cytokines systemic health. |
| url | http://www.journal.adre.ro/particularities-of-some-endogenous-substances-with-humoral-defense-role-in-the-oral-cavity/ |
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