Common Medical and Statistical Problems: The Dilemma of the Sample Size Calculation for Sensitivity and Specificity Estimation

Sample size calculation in biomedical practice is typically based on the problematic Wald method for a binomial proportion, with potentially dangerous consequences. This work highlights the need of incorporating the concept of conditional probability in sample size determination to avoid reduced sam...

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Bibliographic Details
Main Authors: M. Rosário Oliveira, Ana Subtil, Luzia Gonçalves
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/8/8/1258

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