A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients
Abstract Background The objective of this systematic review and meta-analysis was to determine the effect of REBOA, compared to resuscitative thoracotomy, on mortality and among non-compressible torso hemorrhage trauma patients. Methods Relevant articles were identified by a literature search in MED...
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| Format: | Article |
| Language: | English |
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BMC
2017-07-01
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| Series: | World Journal of Emergency Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s13017-017-0142-5 |
| _version_ | 1818418317822525440 |
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| author | Ramiro Manzano Nunez Maria Paula Naranjo Esteban Foianini Paula Ferrada Erika Rincon Herney Andrés García-Perdomo Paola Burbano Juan Pablo Herrera Alberto F. García Carlos A. Ordoñez |
| author_facet | Ramiro Manzano Nunez Maria Paula Naranjo Esteban Foianini Paula Ferrada Erika Rincon Herney Andrés García-Perdomo Paola Burbano Juan Pablo Herrera Alberto F. García Carlos A. Ordoñez |
| author_sort | Ramiro Manzano Nunez |
| collection | DOAJ |
| description | Abstract Background The objective of this systematic review and meta-analysis was to determine the effect of REBOA, compared to resuscitative thoracotomy, on mortality and among non-compressible torso hemorrhage trauma patients. Methods Relevant articles were identified by a literature search in MEDLINE and EMBASE. We included studies involving trauma patients suffering non-compressible torso hemorrhage. Studies were eligible if they evaluated REBOA and compared it to resuscitative thoracotomy. Two investigators independently assessed articles for inclusion and exclusion criteria and selected studies for final analysis. We conducted meta-analysis using random effect models. Results We included three studies in our systematic review. These studies included a total of 1276 patients. An initial analysis found that although lower in REBOA-treated patients, the odds of mortality did not differ between the compared groups (OR 0.42; 95% CI 0.17–1.03). Sensitivity analysis showed that the risk of mortality was significantly lower among patients who underwent REBOA, compared to those who underwent resuscitative thoracotomy (RT) (RR 0.81; 95% CI 0.68–0.97). Conclusion Our meta-analysis, mainly from observational data, suggests a positive effect of REBOA on mortality among non-compressible torso hemorrhage patients. However, these results deserve further investigation. |
| first_indexed | 2024-12-14T12:20:46Z |
| format | Article |
| id | doaj.art-82ed7defbfa14e35b771a0621a4b17fc |
| institution | Directory Open Access Journal |
| issn | 1749-7922 |
| language | English |
| last_indexed | 2024-12-14T12:20:46Z |
| publishDate | 2017-07-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Emergency Surgery |
| spelling | doaj.art-82ed7defbfa14e35b771a0621a4b17fc2022-12-21T23:01:29ZengBMCWorld Journal of Emergency Surgery1749-79222017-07-011211910.1186/s13017-017-0142-5A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patientsRamiro Manzano Nunez0Maria Paula Naranjo1Esteban Foianini2Paula Ferrada3Erika Rincon4Herney Andrés García-Perdomo5Paola Burbano6Juan Pablo Herrera7Alberto F. García8Carlos A. Ordoñez9Clinical Research Center, Fundación Valle del LiliClinical Research Center, Fundación Valle del LiliClinical FoianiniVirginia Commonwealth UniversityClinical Research Center, Fundación Valle del LiliUniversidad del ValleSchool of Medicine, Universidad Javeriana CaliDepartment of Surgery, Brigham and Women’s HospitalUniversidad del ValleUniversidad del ValleAbstract Background The objective of this systematic review and meta-analysis was to determine the effect of REBOA, compared to resuscitative thoracotomy, on mortality and among non-compressible torso hemorrhage trauma patients. Methods Relevant articles were identified by a literature search in MEDLINE and EMBASE. We included studies involving trauma patients suffering non-compressible torso hemorrhage. Studies were eligible if they evaluated REBOA and compared it to resuscitative thoracotomy. Two investigators independently assessed articles for inclusion and exclusion criteria and selected studies for final analysis. We conducted meta-analysis using random effect models. Results We included three studies in our systematic review. These studies included a total of 1276 patients. An initial analysis found that although lower in REBOA-treated patients, the odds of mortality did not differ between the compared groups (OR 0.42; 95% CI 0.17–1.03). Sensitivity analysis showed that the risk of mortality was significantly lower among patients who underwent REBOA, compared to those who underwent resuscitative thoracotomy (RT) (RR 0.81; 95% CI 0.68–0.97). Conclusion Our meta-analysis, mainly from observational data, suggests a positive effect of REBOA on mortality among non-compressible torso hemorrhage patients. However, these results deserve further investigation.http://link.springer.com/article/10.1186/s13017-017-0142-5InjuriesNon-compressible torso hemorrhageREBOAResuscitation strategiesTraumatic shockEndovascular procedures |
| spellingShingle | Ramiro Manzano Nunez Maria Paula Naranjo Esteban Foianini Paula Ferrada Erika Rincon Herney Andrés García-Perdomo Paola Burbano Juan Pablo Herrera Alberto F. García Carlos A. Ordoñez A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients World Journal of Emergency Surgery Injuries Non-compressible torso hemorrhage REBOA Resuscitation strategies Traumatic shock Endovascular procedures |
| title | A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients |
| title_full | A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients |
| title_fullStr | A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients |
| title_full_unstemmed | A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients |
| title_short | A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients |
| title_sort | meta analysis of resuscitative endovascular balloon occlusion of the aorta reboa or open aortic cross clamping by resuscitative thoracotomy in non compressible torso hemorrhage patients |
| topic | Injuries Non-compressible torso hemorrhage REBOA Resuscitation strategies Traumatic shock Endovascular procedures |
| url | http://link.springer.com/article/10.1186/s13017-017-0142-5 |
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