Neuroleptic malignant syndrome: a fatal case with unusual features

<p style="margin-bottom: 0in;"><span style="font-family: Calibri,sans-serif;"><span style="font-size: x-small;">Neuroleptic malignant syndrome is a rare, but potentially life threatening, idiosyncratic reaction primarily related to use of neuroleptic m...

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Bibliographic Details
Main Authors: U. M. Wariyapperuma, C. I.V. Jayasundera
Format: Article
Language:English
Published: Sri Lanka College of Psychiatrists 2014-12-01
Series:Sri Lanka Journal of Psychiatry
Subjects:
Online Access:https://sljpsyc.sljol.info/articles/7823
Description
Summary:<p style="margin-bottom: 0in;"><span style="font-family: Calibri,sans-serif;"><span style="font-size: x-small;">Neuroleptic malignant syndrome is a rare, but potentially life threatening, idiosyncratic reaction primarily related to use of neuroleptic medications. We report a fatal case of neuroleptic malignant syndrome in a 67 year old female with bipolar affective disorder, triggered by recent change of medications. She had marked elevation of creatinine phosphokinase levels, thrombocytopenia and acute kidney injury but no muscle rigidity. Despite early detection, intensive care support and continuous renal replacement therapy, the patient died of rhabdomyolysis induced acute kidney injury and persistent metabolic acidosis.</span></span></p><p style="margin-bottom: 0in;">DOI: <a href="http://dx.doi.org/10.4038/sljpsyc.v5i2.7823">http://dx.doi.org/10.4038/sljpsyc.v5i2.7823</a></p><p style="margin-bottom: 0in;">Sri Lanka Journal of Psychiatry Vol 5(2):35-36</p>
ISSN:2012-6883
2579-2008